Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 4/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TYMS | P04818 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23739497 | 0.90 | THRB (0.33) | THRBGAAPOLBLMNAALDH1A1 | |
| SCHEMBL21848620 | 0.88 | THRB (0.34) | THRBGAAPOLBLMNAALDH1A1 | |
| SCHEMBL23739470 | 0.86 | LMNA (0.36) | THRBGAAPOLBLMNAALDH1A1 | |
| SCHEMBL23739619 | 0.84 | IDO1 (0.36) | POLBLMNAALDH1A1 | |
| SCHEMBL23739919 | 0.84 | IDO1 (0.36) | POLBLMNAALDH1A1 | |
| SCHEMBL23739950 | 0.84 | MEN1 (0.35) | POLBHTTMEN1KMT2A | |
| SCHEMBL23739930 | 0.84 | ITGB2 (0.34) | THRBGAAKMT2A | |
| SCHEMBL23934675 | 0.83 | THRB (0.33) | THRBGAAPOLBLMNAALDH1A1 | |
| SCHEMBL23739853 | 0.82 | HTR7 (0.43) | MAPTMEN1KMT2A | |
| SCHEMBL26443198 | 0.82 | ALDH1A1 (0.36) | THRBGAAPOLBLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020249048-A1 | ALK PROTEIN REGULATOR AND ANTI-TUMOR APPLICATION THEREOF | 上海科技大学 | 2020-12-17 | — | — | WO | disclosed |