Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 15/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.32 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.31 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22791251 | 0.89 | PTGER4 (0.33) | PTGER4PTGER2NPY5REGLN1PTGDR2 | |
| SCHEMBL22791294 | 0.88 | PTGER4 (0.34) | PTGER4PTGER2NPY5RPTGDR2 | |
| SCHEMBL22776455 | 0.86 | HTR4 (0.34) | HTR4KCNH2PTGER4HTR2ANPY5R | |
| SCHEMBL22791540 | 0.81 | GSK3B (0.36) | PTGER4PTGER2HTR2AEGLN1 | |
| SCHEMBL22791483 | 0.81 | FPR1 (0.32) | PTGER4PTGDR2 | |
| SCHEMBL22791412 | 0.80 | PDE4A (0.35) | PTGER4PTGER2 | |
| SCHEMBL22777101 | 0.80 | HTR4 (0.36) | HTR4KCNH2PTGER4NPY5R | |
| SCHEMBL22791408 | 0.79 | P2RX7 (0.37) | PTGER4PTGER2 | |
| SCHEMBL22776609 | 0.79 | LDHA (0.39) | HTR4PTGER4NPY5R | |
| SCHEMBL29527167 | 0.79 | LDHA (0.39) | HTR4PTGER4NPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020251957-A1 | PROSTAGLANDIN E2 RECEPTOR 4 ANTAGONISTS AND USES THEREOF | TEON THERAPEUTICS, INC. (US) | 2020-12-17 | — | — | WO | disclosed |