Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 2/20 | 0.31 |
| ▸ | DRD2 | P14416 | 2/20 | 0.31 |
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.31 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | BCR | P11274 | 1/20 | 0.31 |
| ▸ | CSF1R | P07333 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22791527 | 1.00 | GSK3B (0.38) | GSK3BCRHR1PTGER4OPRL1MAPK10 | |
| SCHEMBL22791540 | 0.92 | GSK3B (0.36) | GSK3BCRHR1PTGER4MAPK10HTR1A | |
| SCHEMBL22776597 | 0.85 | GSK3B (0.38) | GSK3BCRHR1OPRL1MAPK10HTR1A | |
| SCHEMBL29614550 | 0.85 | GSK3B (0.38) | GSK3BCRHR1OPRL1MAPK10HTR1A | |
| SCHEMBL22791483 | 0.82 | FPR1 (0.32) | PTGER4OPRL1 | |
| SCHEMBL22791528 | 0.81 | GSK3B (0.36) | GSK3BCRHR1MAPK10HTR1ADRD2 | |
| SCHEMBL22791491 | 0.79 | P2RX7 (0.37) | OPRL1 | |
| SCHEMBL22791480 | 0.79 | KDM4E (0.32) | PTGER4OPRL1PTGER2 | |
| SCHEMBL22791354 | 0.78 | YTHDC1 (0.46) | GSK3BCRHR1MAPK10HTR1ADRD2 | |
| SCHEMBL22791280 | 0.78 | P2RX7 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020251957-A1 | PROSTAGLANDIN E2 RECEPTOR 4 ANTAGONISTS AND USES THEREOF | TEON THERAPEUTICS, INC. (US) | 2020-12-17 | — | — | WO | disclosed |