Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 6/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | PGK1 | P00558 | 3/20 | 0.51 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3122746 | 0.72 | L3MBTL1 (0.67) | CYP1A2CYP3A4ALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL10555220 | 0.70 | SMN1; SMN2 (0.59) | CYP1A2CYP3A4ALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL22792244 | 0.70 | CYP3A4 (0.55) | CYP1A2CYP3A4ALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL22792275 | 0.70 | MEN1 (0.52) | CYP1A2CYP3A4ALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL22792280 | 0.70 | ALDH1A1 (0.50) | CYP3A4ALDH1A1CYP2C19KDM4EL3MBTL1 | |
| SCHEMBL9786435 | 0.70 | SMN1; SMN2 (0.53) | CYP1A2CYP3A4ALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL10750744 | 0.69 | SMN1; SMN2 (0.53) | CYP1A2CYP3A4ALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL22792621 | 0.69 | CYP1A2 (0.54) | CYP1A2CYP3A4ALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL22792311 | 0.69 | CYP1A2 (0.53) | CYP1A2CYP3A4ALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL10562491 | 0.69 | ALDH1A1 (0.60) | CYP1A2CYP3A4ALDH1A1CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020252229-A2 | INHIBITORS OF SARM1 | DISARM THERAPEUTICS, INC. (US) | 2020-12-17 | — | — | WO | disclosed |