Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 8/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 8/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 7/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.53 |
| ▸ | CLK4 | Q9HAZ1 | 5/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | FYN | P06241 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22792621 | 0.80 | CYP1A2 (0.54) | CYP1A2CYP2D6CYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL22792187 | 0.77 | CYP1A2 (0.53) | CYP1A2CYP2D6CYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL22792326 | 0.77 | PGK1 (0.53) | CYP1A2CYP2D6CYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL3948160 | 0.77 | ALDH1A1 (0.77) | CYP1A2CYP2D6CYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL1108645 | 0.75 | ALDH1A1 (0.65) | CYP1A2CYP2D6CYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL13763288 | 0.74 | ALDH1A1 (0.60) | CYP1A2CYP2D6CYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL22792726 | 0.73 | LTA4H (0.55) | CYP1A2CYP2D6CYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL22031931 | 0.73 | ALDH1A1 (0.56) | CYP1A2CYP3A4ALDH1A1HSD17B10CLK4 | |
| SCHEMBL22792244 | 0.72 | CYP3A4 (0.55) | CYP1A2CYP2D6CYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL22792619 | 0.72 | ALDH1A1 (0.52) | CYP1A2CYP2D6CYP3A4CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020252229-A2 | INHIBITORS OF SARM1 | DISARM THERAPEUTICS, INC. (US) | 2020-12-17 | — | — | WO | disclosed |