Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | GSK3B | P49841 | 1/20 | 0.49 |
| ▸ | PGK1 | P00558 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22792244 | 0.77 | CYP3A4 (0.55) | LTA4HALDH1A1MEN1KMT2APGK1 | |
| SCHEMBL2908596 | 0.77 | ALDH1A1 (0.69) | LTA4HALDH1A1MAPTMEN1PABPC1 | |
| SCHEMBL19312422 | 0.76 | LTA4H (0.60) | LTA4HALDH1A1MAPTMEN1PABPC1 | |
| SCHEMBL3122746 | 0.76 | L3MBTL1 (0.67) | LTA4HALDH1A1MAPTMEN1PABPC1 | |
| SCHEMBL4190213 | 0.75 | BACE1 (0.55) | LTA4HALDH1A1MAPTMEN1PABPC1 | |
| SCHEMBL5605047 | 0.73 | LTA4H (0.82) | LTA4HALDH1A1MAPTMEN1PABPC1 | |
| SCHEMBL22792311 | 0.73 | CYP1A2 (0.53) | LTA4HALDH1A1MEN1KMT2AGSK3B | |
| SCHEMBL22792621 | 0.73 | CYP1A2 (0.54) | LTA4HALDH1A1MEN1KMT2AGSK3B | |
| SCHEMBL2909164 | 0.73 | PGK1 (0.60) | LTA4HALDH1A1MAPTMEN1PABPC1 | |
| SCHEMBL2905635 | 0.73 | MAPT (0.71) | LTA4HALDH1A1MAPTMEN1PABPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020252229-A2 | INHIBITORS OF SARM1 | DISARM THERAPEUTICS, INC. (US) | 2020-12-17 | — | — | WO | disclosed |