Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGK1 | P00558 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 7/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 6/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22792316 | 0.81 | KDM4C (0.53) | PGK1ALDH1A1KDM4ECYP3A4CYP2C19 | |
| SCHEMBL29299459 | 0.80 | THRB (0.50) | CLK4NPC1MEN1KMT2ACACNA2D1 | |
| SCHEMBL22792311 | 0.77 | CYP1A2 (0.53) | PGK1ALDH1A1KDM4EHPGDCYP3A4 | |
| SCHEMBL22792621 | 0.77 | CYP1A2 (0.54) | PGK1ALDH1A1KDM4EHPGDCYP3A4 | |
| SCHEMBL22792187 | 0.76 | CYP1A2 (0.53) | PGK1ALDH1A1KDM4EHPGDCYP3A4 | |
| SCHEMBL7256637 | 0.70 | USP1 (0.59) | PGK1ALDH1A1KDM4ECYP3A4CYP2C19 | |
| SCHEMBL22792726 | 0.70 | LTA4H (0.55) | PGK1ALDH1A1KDM4ECYP3A4CYP2C19 | |
| SCHEMBL25219947 | 0.70 | KDM4C (0.53) | PGK1ALDH1A1KDM4EHPGDCYP3A4 | |
| SCHEMBL31278225 | 0.70 | KDM4C (0.53) | PGK1ALDH1A1KDM4EHPGDCYP3A4 | |
| SCHEMBL21076561 | 0.70 | KDM4C (0.50) | PGK1ALDH1A1KDM4EHPGDCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020252229-A2 | INHIBITORS OF SARM1 | DISARM THERAPEUTICS, INC. (US) | 2020-12-17 | — | — | WO | disclosed |