Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKAG1 | P54619 | 2/20 | 0.41 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.41 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | HAO1 | Q9UJM8 | 2/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | ERN1 | O75460 | 2/20 | 0.36 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.36 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.36 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21296952 | 0.90 | RXRA (0.51) | PRKAG1PRKAA1PRKAB1RXRAALPL | |
| SCHEMBL22795582 | 0.86 | DHODH (0.43) | PRKAG1PRKAA1PRKAB1DHODHHAO1 | |
| SCHEMBL21296847 | 0.85 | PRKAG1 (0.51) | PRKAG1PRKAA1PRKAB1ALPLCA9 | |
| SCHEMBL21296929 | 0.82 | PIN1 (0.49) | PRKAG1PRKAA1PRKAB1ALPLCA9 | |
| SCHEMBL21296956 | 0.81 | HAO1 (0.52) | PRKAG1PRKAA1PRKAB1ALPLCA9 | |
| SCHEMBL22795588 | 0.80 | ERN1 (0.46) | PRKAG1PRKAA1PRKAB1ALPLCA9 | |
| SCHEMBL21296954 | 0.80 | PRKAG1 (0.50) | PRKAG1PRKAA1PRKAB1ALPLCA9 | |
| SCHEMBL29799086 | 0.80 | PRKAG1 (0.50) | PRKAG1PRKAA1PRKAB1ALPLCA9 | |
| SCHEMBL21296848 | 0.78 | PRKAG1 (0.45) | PRKAG1PRKAA1PRKAB1ALPLCA9 | |
| SCHEMBL21296926 | 0.78 | PIN1 (0.47) | PRKAG1PRKAA1PRKAB1RXRACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200390778-A1 | COMPOUNDS AND METHODS FOR TREATING OXALATE-RELATED DISEASES | OXALURX, INC. | 2020-12-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200390778-A1 | COMPOUNDS AND METHODS FOR TREATING OXALATE-RELATED DISEASES | XDH, PNPO, LOX | PRKAG1 2580/4885PRKAA1 2860/4885PRKAB1 2716/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.