Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.46 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | ESD | P10768 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL907700 | 0.82 | HSD11B1 (0.39) | CD274PDCD1SMN1; SMN2GRIN2BPLD1 | |
| SCHEMBL22796281 | 0.80 | ESD (0.53) | CD274PDCD1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL22796296 | 0.80 | CD274 (0.43) | CD274PDCD1SMN1; SMN2GRIN2BPLD1 | |
| SCHEMBL27447779 | 0.78 | CD274 (0.46) | CD274PDCD1SMN1; SMN2GRIN2BCCNA2 | |
| SCHEMBL19866263 | 0.78 | SMN1; SMN2 (0.56) | CD274PDCD1SMN1; SMN2CCNA2CDK2 | |
| SCHEMBL13387492 | 0.75 | MAPT (0.47) | SMN1; SMN2KDM4EALDH1A1CYP1A2HPGD | |
| SCHEMBL22795865 | 0.75 | ESD (0.55) | CD274PDCD1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL19866242 | 0.72 | SMN1; SMN2 (0.40) | CD274PDCD1SMN1; SMN2GRIN2BCCNA2 | |
| SCHEMBL19866302 | 0.69 | ALDH1A1 (0.35) | CD274PDCD1SMN1; SMN2CCNA2CDK2 | |
| SCHEMBL20663324 | 0.68 | PRKCZ (0.41) | SMN1; SMN2KDM4EALDH1A1MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200390100-A1 | SUBSTITUTED N-HETEROCYCLYL- AND N-HETEROARYL-TETRAHYDROPYRIMIDINONES AND THE SALTS THEREOF, AND THE USE OF SAME AS HERBICIDAL ACTIVE SUBSTANCES | BAYER AG (DE) | 2020-12-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200390100-A1 | SUBSTITUTED N-HETEROCYCLYL- AND N-HETEROARYL-TETRAHYDROPYRIMIDINONES AND THE SALTS THEREOF, AND THE USE OF SAME AS HERBICIDAL ACTIVE SUBSTANCES | DDT, NOTUM, AGPS | CD274 4220/4885PDCD1 2109/4885SMN1; SMN2 4626/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.