Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 4/20 | 0.46 |
| ▸ | PDCD1 | Q15116 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | TERT | O14746 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22796294 | 0.78 | CD274 (0.46) | CD274PDCD1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL25178380 | 0.78 | MAPT (0.48) | SMN1; SMN2KDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL22796296 | 0.78 | CD274 (0.43) | CD274PDCD1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL28091311 | 0.77 | HTR3E (0.40) | SMN1; SMN2KDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL22796281 | 0.75 | ESD (0.53) | CD274PDCD1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL27732171 | 0.73 | TERT (0.40) | SMN1; SMN2KDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL22795865 | 0.70 | ESD (0.55) | CD274PDCD1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL28158503 | 0.70 | TERT (0.35) | SMN1; SMN2ALDH1A1MAPTKMT2ANPSR1 | |
| SCHEMBL27712033 | 0.70 | MAPT (0.38) | SMN1; SMN2KDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL27369841 | 0.70 | ALDH1A1 (0.43) | SMN1; SMN2KDM4EALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101001921-A | Cationic pyrazolone dyes method for production thereof and colouring agents for keratin fibres containing said compounds | WELLA AG (DE) | 2007-07-18 | — | — | CN | disclosed |
| CN-1066138-C | 4-(arylaminomethylene)-2,4-dihydro-3-pyrazolones | MERCK PATENT GMBH (DE) | 2001-05-23 | — | — | CN | disclosed |
| CN-1141291-A | 4-(Arylaminomethylene)-2,4-dihydro-3-pyrazolones | MERCK PATENT GMBH (DE) | 1997-01-29 | — | — | CN | disclosed |