Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 6/20 | 0.54 |
| ▸ | CYP11B1 | P15538 | 5/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | GRM5 | P41594 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | EP300 | Q09472 | 1/20 | 0.45 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL306879 | 0.89 | GAA (0.58) | CYP11B2CYP11B1HDAC1DRD2DRD3 | |
| SCHEMBL31700253 | 0.89 | GAA (0.58) | CYP11B2CYP11B1HDAC1DRD2DRD3 | |
| SCHEMBL5606442 | 0.88 | GAA (0.53) | CYP11B2CYP11B1HDAC1DRD2DRD3 | |
| SCHEMBL31500101 | 0.88 | GAA (0.53) | CYP11B2CYP11B1HDAC1DRD2DRD3 | |
| SCHEMBL22144575 | 0.80 | CRBN (0.65) | CYP11B2CYP11B1HDAC1DRD2DRD3 | |
| SCHEMBL6068510 | 0.80 | CYP11B2 (0.47) | CYP11B2CYP11B1HDAC1DRD2DRD3 | |
| SCHEMBL5740638 | 0.78 | PTGS2 (0.48) | CYP11B2CYP11B1HDAC1DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL30621177 | 0.78 | CRBN (0.63) | CYP11B2CYP11B1HDAC1DRD2DRD3 | |
| SCHEMBL5765571 | 0.78 | CHRNB2 (0.51) | CYP11B2CYP11B1HDAC1DRD2DRD3 | |
| Trifluoroacetic Acid SCHEMBL30547501 | 0.78 | ALDH1A1 (0.50) | CYP11B2CYP11B1HDAC1DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020252151-A1 | COT MODULATORS AND METHODS OF USE THEREOF | GILEAD SCIENCES, INC. (US) | 2020-12-17 | — | — | WO | disclosed |