Known targets — ChEMBL curated mechanism
KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2
The experimentally established mechanism targets of Guanidine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.65 |
| ▸ | MMP7 | P09237 | 2/20 | 0.65 |
| ▸ | MMP14 | P50281 | 2/20 | 0.65 |
| ▸ | HSD11B1 | P28845 | 6/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MMP1 | P03956 | 1/20 | 0.49 |
| ▸ | MMP3 | P08254 | 1/20 | 0.49 |
| ▸ | MMP9 | P14780 | 1/20 | 0.49 |
| ▸ | MMP13 | P45452 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL270706 | 0.90 | MMP2 (0.77) | MMP2MMP7MMP14HSD11B1KMT2A | |
| Ammonia Solution, Strong SCHEMBL20473391 | 0.88 | MMP2 (0.74) | MMP2MMP7MMP14HSD11B1KMT2A | |
| SCHEMBL6553421 | 0.88 | MMP2 (0.74) | MMP2MMP7MMP14HSD11B1KMT2A | |
| SCHEMBL6553661 | 0.88 | MMP2 (0.74) | MMP2MMP7MMP14HSD11B1KMT2A | |
| Ammonia Solution, Strong SCHEMBL20473392 | 0.88 | MMP2 (0.74) | MMP2MMP7MMP14HSD11B1KMT2A | |
| Ammonia Solution, Strong SCHEMBL8418478 | 0.88 | MMP2 (0.74) | MMP2MMP7MMP14HSD11B1KMT2A | |
| SCHEMBL6552246 | 0.88 | MMP2 (0.74) | MMP2MMP7MMP14HSD11B1KMT2A | |
| SCHEMBL6552547 | 0.88 | MMP2 (0.74) | MMP2MMP7MMP14HSD11B1KMT2A | |
| SCHEMBL9136704 | 0.84 | HSD11B1 (0.53) | MMP2MMP7MMP14HSD11B1KMT2A | |
| Guanidine SCHEMBL8772768 | 0.84 | ALDH1A1 (0.69) | MMP2MMP7MMP14HSD11B1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 240 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-H691-H | CONTAINING IMIDOTHIOESTER COMPOUND AND BASE PRECURSOR; HEAT RESISTANCE, STABILITY, ANTIFOGGING AGENT | FUJI PHOTO FILM CO., LTD. (JP) | 1989-10-03 | — | — | US | claimed |
| CN-122085595-A | Colored photosensitive resin composition and application thereof | — | 2026-05-26 | — | — | CN | disclosed |
| US-20260022202-A1 | UV-CURABLE COMPOSITION AND USE THEREOF | DOW TORAY CO LTD (JP) | 2026-01-22 | — | — | US | disclosed |
| US-12339586-B2 | Photocurable resin composition containing self-crosslinkable polymer | NISSAN CHEMICAL CORPORATION (JP) | 2025-06-24 | — | — | US | disclosed |
| US-20250172869-A1 | WAFER END PROTECTIVE-FILM FORMING COMPOSITION FOR SEMICONDUCTOR MANUFACTURING | NISSAN CHEMICAL CORPORATION (JP) | 2025-05-29 | — | — | US | disclosed |
| US-20250116936-A1 | PHOTOCURABLE RESIN COMPOSITION CONTAINING SELF-CROSSLINKABLE POLYMER | NISSAN CHEMICAL CORPORATION (JP) | 2025-04-10 | — | — | US | disclosed |
| EP-4492142-A1 | WAFER EDGE PROTECTIVE FILM-FORMING COMPOSITION FOR SEMICONDUCTOR MANUFACTURING | Nissan Chemical Corporation (JP) | 2025-01-15 | — | — | EP | disclosed |
| US-20250014901-A1 | WAFER EDGE PROTECTIVE FILM-FORMING COMPOSITION FOR SEMICONDUCTOR MANUFACTURING | NISSAN CHEMICAL CORPORATION (JP) | 2025-01-09 | — | — | US | disclosed |
| US-20250011507-A1 | POLYCYCLIC AROMATIC HYDROCARBON PHOTOCURABLE RESIN COMPOSITION | NISSAN CHEMICAL CORPORATION (JP) | 2025-01-09 | — | — | US | disclosed |
| EP-4485077-A1 | PHOTOCURABLE RESIN COMPOSITION CONTAINING SELF-CROSSLINKING POLYMER | Nissan Chemical Corporation (JP) | 2025-01-01 | — | — | EP | disclosed |
| US-4640892-A | STORAGE STABLE BASE PRECURSOR | FUJI PHOTO FILM CO., LTD. (JP) | 1987-02-03 | — | — | US | disclosed |
| US-4637975-A | CATIONIC DYE | FUJI PHOTO FILM CO., LTD. (JP) | 1987-01-20 | — | — | US | disclosed |
| US-4636462-A | PHOTOTHERMOGRAPHY; STORAGE STABLE BASE PRECURSOR | FUJI PHOTO FILM CO., LTD. (JP) | 1987-01-13 | — | — | US | disclosed |
| US-4629676-A | DRY PROCESSING | FUJI PHOTO FILM CO., LTD. (JP) | 1986-12-16 | — | — | US | disclosed |
| EP-0202490-A1 | Method for forming a polymer image and image recording material therefor | FUJI PHOTO FILM CO., LTD. (JP) | 1986-11-26 | — | — | EP | disclosed |
| EP-0200011-A1 | Heat-developable light-sensitive material | FUJI PHOTO FILM CO., LTD. (JP) | 1986-11-05 | — | — | EP | disclosed |
| US-4619888-A | HIGH DENSITY IMAGES; IMPROVED SHELF LIFE | FUJI PHOTO FILM CO., LTD. (JP) | 1986-10-28 | — | — | US | disclosed |
| EP-0192272-A2 | Color light-sensitive material | FUJI PHOTO FILM CO., LTD. (JP) | 1986-08-27 | — | — | EP | disclosed |
| EP-0174634-A2 | Image forming method | FUJI PHOTO FILM CO., LTD. (JP) | 1986-03-19 | — | — | EP | disclosed |
| US-4156610-A | Copper physical development using heterocyclic ligand copper(I) complexes | EASTMAN KODAK COMPANY (US) | 1979-05-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260022202-A1 | UV-CURABLE COMPOSITION AND USE THEREOF | IDUA, SEM1, ARSA | MMP2 978/4885MMP7 1397/4885MMP14 837/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.