Known targets — ChEMBL curated mechanism
KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2
The experimentally established mechanism targets of Guanidine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.69 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | MMP2 | P08253 | 1/20 | 0.54 |
| ▸ | MMP7 | P09237 | 1/20 | 0.54 |
| ▸ | MMP14 | P50281 | 1/20 | 0.54 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL924405 | 0.91 | ALDH1A1 (0.69) | ALDH1A1RECQLMMP2MMP7MMP14 | |
| SCHEMBL10338421 | 0.89 | ALDH1A1 (0.67) | ALDH1A1RECQLMMP2MMP7MMP14 | |
| SCHEMBL10338418 | 0.89 | ALDH1A1 (0.67) | ALDH1A1RECQLMMP2MMP7MMP14 | |
| Acetic Acid SCHEMBL8984837 | 0.87 | ALDH1A1 (0.65) | ALDH1A1RECQLMMP2MMP7MMP14 | |
| Guanidine SCHEMBL2286558 | 0.86 | MMP2 (0.54) | ALDH1A1MMP2MMP7MMP14HSD11B1 | |
| SCHEMBL6651299 | 0.86 | ALDH1A1 (0.62) | ALDH1A1RECQLMMP2MMP7MMP14 | |
| Guanidine SCHEMBL2279843 | 0.84 | MMP2 (0.65) | MMP2MMP7MMP14HSD11B1CA12 | |
| Guanidine SCHEMBL2289728 | 0.83 | NPC1 (0.69) | ALDH1A1MMP2MMP7MMP14HSD11B1 | |
| SCHEMBL608774 | 0.82 | ALDH1A1 (1.00) | ALDH1A1RECQLHSD11B1MAPTLMNA | |
| Guanidine SCHEMBL8415495 | 0.79 | HSD11B1 (0.58) | ALDH1A1MMP2MMP7MMP14HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122085595-A | Colored photosensitive resin composition and application thereof | — | 2026-05-26 | — | — | CN | disclosed |
| CN-122085594-A | Positive coloring photosensitive composition and application thereof | — | 2026-05-26 | — | — | CN | disclosed |
| CN-116262827-A | Polyimide precursor resin, photosensitive resin composition and application thereof | 北京鼎材科技有限公司 | 2023-06-16 | — | — | CN | disclosed |
| CN-115128898-A | Photosensitive resin composition and application thereof | 北京鼎材科技有限公司 | 2022-09-30 | — | — | CN | disclosed |
| CN-114967324-A | Diamine compound, resin prepared from same, photosensitive resin composition and application | 北京鼎材科技有限公司 | 2022-08-30 | — | — | CN | disclosed |
| CN-114967325-A | Diamine compound, resin prepared from same, photosensitive resin composition and application | 北京鼎材科技有限公司 | 2022-08-30 | — | — | CN | disclosed |
| EP-0659581-B1 | Stabilized thermal-dye-bleach constructions | MINNESOTA MINING & MFG (US) | 1997-10-15 | — | — | EP | disclosed |
| EP-0659581-A2 | Stabilized thermal-dye-bleach constructions | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-06-28 | — | — | EP | disclosed |
| US-5395747-A | Polylactones as stabilizers in antihalation systems where an anion is thermally generated to decolor dyes formed by scattered light | MINNESOTA MINING & MANUFACTURING COMPANY (US) | 1995-03-07 | — | — | US | disclosed |