Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13086281 | 0.84 | LMNA (0.34) | LMNA | |
| SCHEMBL25045618 | 0.78 | — | — | |
| SCHEMBL23197727 | 0.75 | ALDH1A1 (0.31) | — | |
| SCHEMBL17903581 | 0.71 | ALOX15 (0.44) | LMNA | |
| SCHEMBL22479214 | 0.68 | SMN1; SMN2 (0.35) | — | |
| SCHEMBL17561679 | 0.67 | TBXAS1 (0.40) | LMNA | |
| SCHEMBL1645600 | 0.65 | NPC1 (0.47) | — | |
| SCHEMBL10140801 | 0.64 | ALDH1A1 (0.38) | LMNA | |
| SCHEMBL26262656 | 0.63 | ACHE (0.32) | — | |
| SCHEMBL11943531 | 0.63 | LMNA (0.33) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020252353-A1 | AMINO ACID TRANSPORT INHIBITORS AND THE USES THEREOF | VANDERBILT UNIVERSITY (US) | 2020-12-17 | — | — | WO | disclosed |