Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.46 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22800302 | 0.94 | KDM4C (0.45) | ALDH1A1L3MBTL1PTPN11KDM4CKDM4E | |
| SCHEMBL22800284 | 0.87 | SLC6A3 (0.43) | ALDH1A1L3MBTL1PTPN11KDM4CKDM4E | |
| SCHEMBL22800304 | 0.82 | TSHR (0.43) | ALDH1A1L3MBTL1KDM4CKDM4EMEN1 | |
| SCHEMBL22800183 | 0.77 | PTPN11 (0.46) | ALDH1A1L3MBTL1PTPN11KDM4ECYP4F2 | |
| Hydrochloric Acid SCHEMBL9177131 | 0.77 | ALDH1A1 (0.55) | ALDH1A1L3MBTL1PTPN11KDM4EDHODH | |
| SCHEMBL22800871 | 0.76 | ALDH1A1 (0.45) | ALDH1A1L3MBTL1PTPN11KDM4CKDM4E | |
| SCHEMBL18763585 | 0.76 | ALDH1A1 (0.53) | ALDH1A1L3MBTL1PTPN11HDAC3HDAC4 | |
| SCHEMBL22799652 | 0.75 | KDM4E (0.44) | PTPN11KDM4CKDM4E | |
| SCHEMBL14554479 | 0.74 | CCR1 (0.44) | ALDH1A1L3MBTL1HDAC3HDAC4HDAC1 | |
| SCHEMBL8604099 | 0.73 | PTPN11 (0.59) | ALDH1A1L3MBTL1PTPN11DHODHHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200392157-A1 | CALPAIN MODULATORS AND THERAPEUTIC USES THEREOF | Knobbe, Martens, Olson & Bear, LLP | 2020-12-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200392157-A1 | CALPAIN MODULATORS AND THERAPEUTIC USES THEREOF | CAPNS1, CAPN2, CAPN1 | ALDH1A1 3918/4885L3MBTL1 3891/4885PTPN11 4064/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.