Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | CA7 | P43166 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 3/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.35 |
| ▸ | APLNR | P35414 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 5/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3180767 | 0.92 | DGAT1 (0.47) | DGAT1TDP1CA1CA2CA7 | |
| SCHEMBL3936414 | 0.92 | DGAT1 (0.47) | DGAT1TDP1CA1CA2CA7 | |
| SCHEMBL4549806 | 0.92 | DGAT1 (0.47) | DGAT1TDP1CA1CA2CA7 | |
| SCHEMBL1164425 | 0.85 | PKM (0.50) | TDP1CA1CA7MEN1KMT2A | |
| SCHEMBL20221685 | 0.84 | TDP1 (0.42) | DGAT1TDP1CA1CA2CA7 | |
| SCHEMBL201901 | 0.84 | TDP1 (0.42) | DGAT1TDP1CA1CA2CA7 | |
| SCHEMBL16409143 | 0.84 | TDP1 (0.42) | DGAT1TDP1CA1CA2CA7 | |
| SCHEMBL1486204 | 0.84 | TDP1 (0.42) | DGAT1TDP1CA1CA2CA7 | |
| SCHEMBL16409166 | 0.84 | TDP1 (0.42) | DGAT1TDP1CA1CA2CA7 | |
| SCHEMBL2129742 | 0.84 | TDP1 (0.42) | DGAT1TDP1CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8580747-B2 | Cyclic natriuretic peptide constructs | PALATIN TECHNOLOGIES, INC. (US) | 2013-11-12 | — | — | US | disclosed |
| US-7989649-B2 | Tumor imaging compounds | EMORY UNIVERSITY (US) | 2011-08-02 | — | — | US | disclosed |
| US-7989649-B2 | Tumor imaging compounds | EMORY UNIVERSITY (US) | 2011-08-02 | — | — | US | disclosed |
| EP-1499584-B1 | TUMOR IMAGING COMPOUNDS | UNIV EMORY (US) | 2010-08-18 | — | — | EP | disclosed |
| US-20090240041-A1 | TUMOR IMAGING COMPOUNDS | EMORY UNIVERSITY (US) | 2009-09-24 | — | — | US | disclosed |
| US-7544715-B2 | Tumor imaging compounds | EMORY UNIVERSITY (US) | 2009-06-09 | — | — | US | disclosed |
| EP-1499584-A4 | TUMOR IMAGING COMPOUNDS | UNIV EMORY (US) | 2007-08-15 | — | — | EP | disclosed |
| US-20050192458-A1 | radiolabeled amino acids for use as metabolic tracers to image tumors using positron emission tomography; combine the advantageous properties of alpha -aminoisobutyric acid analogs namely, their rapid uptake and prolonged retention in tumors with the properties of halogen sustituents | EMORY UNIVERSITY | 2005-09-01 | — | — | US | disclosed |
| EP-1499584-A2 | TUMOR IMAGING COMPOUNDS | Emory University (US) | 2005-01-26 | — | — | EP | disclosed |
| WO-2003093412-A2 | TUMOR IMAGING COMPOUNDS | EMORY UNIVERSITY (US) | 2003-11-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050192458-A1 | radiolabeled amino acids for use as metabolic tracers to image tumors using positron emission tomography; combine the advantageous properties of alpha -aminoisobutyric acid analogs namely, their rapid uptake and prolonged retention in tumors with the properties of halogen sustituents | SLC43A1, SLC1A5, SSTR4 | DGAT1 4150/4885TDP1 4820/4885CA1 252/4885 |
| US-20090240041-A1 | TUMOR IMAGING COMPOUNDS | AADAT, MKI67, SSTR1 | DGAT1 4582/4885TDP1 4506/4885CA1 113/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.