Sugi Predict

Sugi Predict / Compounds / SCHEMBL201901

SCHEMBL201901

SCHEMBL201901

CC(C)(C)OC(=O)NC(C)(CO)C(=O)O

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 1/20 0.42
▸ MEN1 O00255 1/20 0.40
▸ GAA P10253 1/20 0.40
▸ KMT2A Q03164 1/20 0.40
▸ CTSK P43235 9/20 0.38
▸ CTSS P25774 7/20 0.38
▸ NAALAD2 Q9Y3Q0 1/20 0.37
▸ CA1 P00915 3/20 0.37
▸ CA7 P43166 3/20 0.37
▸ CA2 P00918 2/20 0.37
▸ CTSL P07711 1/20 0.36
▸ CTSB P07858 1/20 0.36
▸ CA12 O43570 3/20 0.35
▸ CA14 Q9ULX7 3/20 0.35
▸ APLNR P35414 1/20 0.35
▸ DGAT1 O75907 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2129742 1.00 TDP1 (0.42) TDP1MEN1GAAKMT2ACTSK
SCHEMBL1486204 1.00 TDP1 (0.42) TDP1MEN1GAAKMT2ACTSK
SCHEMBL28065098 0.85 TDP1 (0.43) TDP1MEN1GAAKMT2ACTSK
SCHEMBL3936414 0.84 DGAT1 (0.47) TDP1MEN1GAAKMT2ACTSK
SCHEMBL2837383 0.84 CTSK (0.45) TDP1MEN1GAAKMT2ACTSK
SCHEMBL20221685 0.84 TDP1 (0.42) TDP1MEN1GAAKMT2ACTSK
SCHEMBL1979479 0.84 CTSK (0.45) TDP1MEN1GAAKMT2ACTSK
SCHEMBL2280101 0.84 DGAT1 (0.42) TDP1MEN1GAAKMT2ACTSK
SCHEMBL3180767 0.84 DGAT1 (0.47) TDP1MEN1GAAKMT2ACTSK
SCHEMBL16409166 0.84 TDP1 (0.42) TDP1MEN1GAAKMT2ACTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025111414-A1 TRPM3-MODULATING BENZOFURAN DERIVATIVES KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2025-05-30 — — WO disclosed
CN-113825748-A Antimicrobial compounds and methods 库扎环球有限责任公司 2021-12-21 — — CN disclosed
US-20210300940-A1 TLR7/8 ANTAGONISTS AND USES THEREOF MERCK PATENT GMBH (DE) 2021-09-30 — — US disclosed
EP-3830080-A1 TLR7/8 ANTAGONISTS AND USES THEREOF Merck Patent GmbH (DE) 2021-06-09 — — EP disclosed
CN-112513024-A TLR7/8 antagonists and uses thereof 默克专利股份公司 2021-03-16 — — CN disclosed
WO-2020025517-A1 TLR7/8 ANTAGONISTS AND USES THEREOF MERCK PATENT GMBH (DE) 2020-02-06 — — WO disclosed
US-10414731-B2 Substituted oxopyridine derivatives BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2019-09-17 — — US disclosed
US-20180346424-A1 SUBSTITUTED OXOPYRIDINE DERIVATIVES BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2018-12-06 — — US disclosed
US-20180319798-A1 1,3,4,8-Tetrahydro-2H-Pyrido[1,2-a]Pyrazine Derivative and Use of the Same as HIV Integrase Inhibitor JAPAN TOBACCO INC. (JP) 2018-11-08 — — US disclosed
EP-3197880-B1 SUBSTITUTED OXOPYRIDINE DERIVATIVES WITH ANTI-INFLAMMATORY AND ANTI-THROMBOTIC EFFECT Bayer Pharma AG (DE) 2018-10-24 — — EP disclosed
US-20070260040-A1 Amino Acid Surrogates for Peptidic Constructs PALATIN TECHNOLOGIES, INC. (US) 2007-11-08 — — US disclosed
US-20070232546-A1 Linear Natriuretic Peptide Constructs PALATIN TECHNOLOGIES, INC. (US) 2007-10-04 — — US disclosed
CN-101018761-A Methods and compositions for modulating sphingosine-1-phosphate (S1P) receptor activity PRAECIS PHARM INC (US) 2007-08-15 — — CN disclosed
US-20060211756-A1 Novel heterocycle derivatives useful as selective androgen receptor modulators (SARMs) JANSSEN PHARMACEUTICA N.V. (BE) 2006-09-21 — — US disclosed
CN-1745071-A Novel ethylenediamine derivative DAIICHI SEIYAKU CO (JP) 2006-03-08 — — CN disclosed
EP-0862464-A4 AMINO ACID ANALOGS FOR TUMOR IMAGING UNIV EMORY (US) 2001-07-25 — — EP disclosed
US-5817776-A TECHNETIUM 99 COMPLEXES, SINGLE PHOTON EMISSION TOMOGRAPHY EMORY UNIVERSITY (US) 1998-10-06 — — US disclosed
US-5808146-A Amino acid analogs for tumor imaging EMORY UNIVERSITY (US) 1998-09-15 — — US disclosed
EP-0862464-A1 AMINO ACID ANALOGS FOR TUMOR IMAGING EMORY UNIVERSITY (US) 1998-09-09 — — EP disclosed
WO-1997017092-A1 AMINO ACID ANALOGS FOR TUMOR IMAGING EMORY UNIVERSITY (US) 1997-05-15 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180319798-A1 1,3,4,8-Tetrahydro-2H-Pyrido[1,2-a]Pyrazine Derivative and Use of the Same as HIV Integrase Inhibitor IMPA1, IMPDH1, TYMP TDP1 163/4885MEN1 4734/4885GAA 1576/4885
US-20060211756-A1 Novel heterocycle derivatives useful as selective androgen receptor modulators (SARMs) AR, NR5A1, NR5A2 TDP1 4079/4885MEN1 3896/4885GAA 3806/4885
US-10414731-B2 Substituted oxopyridine derivatives OGFOD1, PNPO, PTGIS TDP1 267/4885MEN1 2095/4885GAA 1903/4885
US-20070260040-A1 Amino Acid Surrogates for Peptidic Constructs ARGLU1, ARG1, QRFPR TDP1 4227/4885MEN1 818/4885GAA 4446/4885
US-20070232546-A1 Linear Natriuretic Peptide Constructs NPR1, NPR3, NPPA TDP1 2975/4885MEN1 1876/4885GAA 3999/4885
US-20180346424-A1 SUBSTITUTED OXOPYRIDINE DERIVATIVES OGFOD1, PNPO, VASP TDP1 266/4885MEN1 2865/4885GAA 1872/4885
US-20210300940-A1 TLR7/8 ANTAGONISTS AND USES THEREOF TLR7, TLR8, TLR9 TDP1 1084/4885MEN1 4681/4885GAA 857/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.