Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 5/20 | 0.62 |
| ▸ | EGFR | P00533 | 3/20 | 0.60 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | IMPDH1 | P20839 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6154479 | 0.81 | IMPDH2 (0.60) | IMPDH2EGFRERBB2ALDH1A1IMPDH1 | |
| SCHEMBL7293099 | 0.80 | ALDH1A1 (0.56) | IMPDH2ALDH1A1LMNAIMPDH1RAB9A | |
| SCHEMBL22801110 | 0.78 | KMT2A (0.54) | EGFRERBB2ALDH1A1MAPTGAA | |
| SCHEMBL11034676 | 0.76 | ALDH1A1 (0.64) | ALDH1A1MAPTLMNAGAARAB9A | |
| SCHEMBL22801100 | 0.76 | MEN1 (0.55) | ALDH1A1MAPTLMNAGAARAB9A | |
| SCHEMBL6382421 | 0.76 | EGFR (1.00) | EGFRERBB2 | |
| SCHEMBL7001839 | 0.74 | ALDH1A1 (0.65) | IMPDH2ALDH1A1LMNAIMPDH1MEN1 | |
| SCHEMBL5716429 | 0.74 | IMPDH2 (0.73) | IMPDH2ALDH1A1MAPTGAAPOLB | |
| SCHEMBL5716434 | 0.74 | IMPDH2 (0.72) | IMPDH2ALDH1A1MAPTLMNAGAA | |
| SCHEMBL13465390 | 0.74 | RAB9A (0.55) | ALDH1A1MAPTLMNAPOLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200399264-A1 | 4-SUBSTITUTED-2-THIAZOLE AMIDES AS ANTIVIRAL AGENTS | NATIONAL INSTITUTES OF HEALTH | 2020-12-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200399264-A1 | 4-SUBSTITUTED-2-THIAZOLE AMIDES AS ANTIVIRAL AGENTS | MAVS, ZC3HAV1, EIF2AK2 | IMPDH2 321/4885EGFR 4152/4885ERBB2 2237/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.