Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 4/20 | 0.60 |
| ▸ | MAP2K1 | Q02750 | 4/20 | 0.55 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.50 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.49 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.49 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.49 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.49 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.49 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.49 |
| ▸ | AR | P10275 | 6/20 | 0.49 |
| ▸ | PGR | P06401 | 1/20 | 0.49 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.48 |
| ▸ | IMPDH1 | P20839 | 2/20 | 0.47 |
| ▸ | IDH1 | O75874 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | RAF1 | P04049 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.45 |
| ▸ | SRC | P12931 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25374578 | 0.90 | ALDH1A1 (0.57) | IMPDH2MAP2K1CSNK2A1PRKCQIMPDH1 | |
| SCHEMBL6157998 | 0.84 | IMPDH2 (0.51) | IMPDH2MAP2K1PSEN1PSEN2APH1B | |
| SCHEMBL22801065 | 0.81 | IMPDH2 (0.62) | IMPDH2IMPDH1ALDH1A1EGFRERBB2 | |
| SCHEMBL30962445 | 0.80 | IMPDH2 (0.54) | IMPDH2ARPGRPRKCQIMPDH1 | |
| SCHEMBL18055564 | 0.80 | IMPDH2 (0.54) | IMPDH2ARPGRPRKCQIMPDH1 | |
| SCHEMBL8597483 | 0.79 | MEN1 (0.62) | ARALDH1A1 | |
| SCHEMBL425574 | 0.78 | IMPDH2 (0.52) | IMPDH2ARPGRIMPDH1IDH1 | |
| SCHEMBL6244338 | 0.78 | IMPDH2 (0.65) | IMPDH2MAP2K1PSEN1PSEN2APH1B | |
| SCHEMBL12653297 | 0.78 | MEN1 (0.53) | IMPDH2ARALDH1A1 | |
| Hydrochloric Acid SCHEMBL551861 | 0.77 | IMPDH2 (0.51) | IMPDH2ARPGRIMPDH1IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050182040-A1 | Benzamide derivatives | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2005-08-18 | — | — | US | disclosed |
| EP-1500643-A1 | BENZAMIDE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2005-01-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050182040-A1 | Benzamide derivatives | ROCK1, ROCK2, NHERF1 | IMPDH2 2157/4885MAP2K1 430/4885CSNK2A1 1896/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.