Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.73 |
| ▸ | NPC1 | O15118 | 6/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.66 |
| ▸ | MAPT | P10636 | 6/20 | 0.62 |
| ▸ | MEN1 | O00255 | 4/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.62 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.62 |
| ▸ | RELA | Q04206 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | AR | P10275 | 1/20 | 0.61 |
| ▸ | GFER | P55789 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | HK1 | P19367 | 1/20 | 0.59 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.59 |
| ▸ | LTA4H | P09960 | 4/20 | 0.54 |
| ▸ | FBP1 | P09467 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6256294 | 0.85 | RAB9A (1.00) | RAB9ANPC1ALDH1A1MAPTMEN1 | |
| SCHEMBL235435 | 0.84 | LTA4H (0.67) | RAB9ANPC1ALDH1A1MAPTMEN1 | |
| Iodide SCHEMBL5464284 | 0.83 | RAB9A (0.97) | RAB9ANPC1ALDH1A1MAPTMEN1 | |
| Iodide SCHEMBL5459815 | 0.83 | RAB9A (0.97) | RAB9ANPC1ALDH1A1MAPTMEN1 | |
| SCHEMBL1399840 | 0.83 | ALDH1A1 (0.76) | RAB9ANPC1ALDH1A1MAPTMEN1 | |
| SCHEMBL8598725 | 0.83 | ALDH1A1 (0.55) | RAB9ANPC1ALDH1A1MAPTMEN1 | |
| Iodide SCHEMBL5460208 | 0.82 | RAB9A (0.87) | RAB9ANPC1ALDH1A1MAPTMEN1 | |
| Bromide SCHEMBL8359230 | 0.82 | ALDH1A1 (0.55) | RAB9ANPC1ALDH1A1MAPTMEN1 | |
| SCHEMBL44869 | 0.80 | ALDH1A1 (1.00) | RAB9ANPC1ALDH1A1MAPTMEN1 | |
| SCHEMBL15580546 | 0.80 | MAPT (0.59) | RAB9ANPC1ALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200399264-A1 | 4-SUBSTITUTED-2-THIAZOLE AMIDES AS ANTIVIRAL AGENTS | NATIONAL INSTITUTES OF HEALTH | 2020-12-24 | — | — | US | disclosed |
| US-20200399264-A1 | 4-SUBSTITUTED-2-THIAZOLE AMIDES AS ANTIVIRAL AGENTS | NATIONAL INSTITUTES OF HEALTH | 2020-12-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200399264-A1 | 4-SUBSTITUTED-2-THIAZOLE AMIDES AS ANTIVIRAL AGENTS | MAVS, ZC3HAV1, EIF2AK2 | RAB9A 1589/4885NPC1 1860/4885ALDH1A1 384/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.