Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.54 |
| ▸ | HRH1 | P35367 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | CCR3 | P51677 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22802252 | 0.98 | ALDH1A1 (0.66) | ALDH1A1LMNAPOLBPLA2G2ANPC1 | |
| SCHEMBL22790774 | 0.93 | ALDH1A1 (0.68) | ALDH1A1LMNAPOLBPLA2G2ANPC1 | |
| SCHEMBL22790776 | 0.86 | RAB9A (0.57) | ALDH1A1LMNAPOLBPLA2G2ANPC1 | |
| Hydrochloric Acid SCHEMBL10502877 | 0.86 | LMNA (0.67) | ALDH1A1LMNAPOLBGAAMEN1 | |
| SCHEMBL22802248 | 0.86 | ALDH1A1 (0.72) | ALDH1A1LMNAPOLBGAAMEN1 | |
| SCHEMBL15800706 | 0.85 | CCR3 (0.70) | LMNAPOLBSIGMAR1KDM4ECCR3 | |
| SCHEMBL12040820 | 0.85 | CCR3 (0.70) | LMNAPOLBSIGMAR1KDM4ECCR3 | |
| SCHEMBL8723260 | 0.85 | CCR3 (0.70) | LMNAPOLBSIGMAR1KDM4ECCR3 | |
| SCHEMBL22790783 | 0.84 | ALDH1A1 (0.58) | ALDH1A1LMNAPOLBNPC1RAB9A | |
| SCHEMBL4555241 | 0.83 | ALDH1A1 (0.60) | ALDH1A1LMNAPLA2G2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020251969-A1 | SMARCA DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2020-12-17 | — | — | WO | disclosed |