Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 10/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 8/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 7/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.44 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.44 |
| ▸ | SLC22A1 | O15245 | 3/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | SCN1A | P35498 | 2/20 | 0.44 |
| ▸ | MRGPRX2 | Q96LB1 | 2/20 | 0.44 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.44 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13361592 | 0.84 | GRIN1 (0.47) | OPRM1OPRK1SIGMAR1GRIN2DGRIN3B | |
| SCHEMBL26232267 | 0.84 | GRIN1 (0.47) | OPRM1OPRK1SIGMAR1GRIN2DGRIN3B | |
| SCHEMBL10066629 | 0.82 | OPRM1 (0.48) | OPRM1OPRD1OPRK1SIGMAR1GRIN2D | |
| SCHEMBL18458897 | 0.81 | OPRM1 (0.47) | OPRM1OPRD1OPRK1SIGMAR1GRIN2D | |
| SCHEMBL24224451 | 0.80 | SLC6A4 (0.49) | OPRM1OPRK1SIGMAR1GRIN2DGRIN3B | |
| SCHEMBL19199079 | 0.80 | DRD2 (0.40) | OPRM1OPRD1OPRK1DRD2DRD4 | |
| SCHEMBL22368457 | 0.79 | SIGMAR1 (0.48) | OPRM1OPRD1OPRK1SIGMAR1MRGPRX2 | |
| SCHEMBL18236060 | 0.79 | OPRD1 (0.47) | OPRM1OPRD1OPRK1 | |
| SCHEMBL10198744 | 0.77 | OPRM1 (0.43) | OPRM1OPRD1OPRK1SIGMAR1GRIN2D | |
| SCHEMBL16015669 | 0.74 | OPRM1 (0.45) | OPRM1OPRD1OPRK1SIGMAR1GRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11234975-B2 | Levorphanol prodrugs and processes for making and using them | KEMPHARM, INC. (US) | 2022-02-01 | — | — | US | disclosed |
| US-20210002226-A1 | LEVORPHANOL PRODRUGS AND PROCESSES FOR MAKING AND USING THEM | ALTER DOMUS (US) LLC | 2021-01-07 | — | — | US | disclosed |
| US-20200390757-A1 | LEVORPHANOL PRODRUGS AND PROCESSES FOR MAKING AND USING THEM | ALTER DOMUS (US) LLC | 2020-12-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200390757-A1 | LEVORPHANOL PRODRUGS AND PROCESSES FOR MAKING AND USING THEM | OPRM1, OPRL1, OPRK1 | OPRM1 1/4885OPRD1 4/4885OPRK1 3/4885 |
| US-11234975-B2 | Levorphanol prodrugs and processes for making and using them | OPRM1, OPRL1, OPRK1 | OPRM1 1/4885OPRD1 4/4885OPRK1 3/4885 |
| US-20210002226-A1 | LEVORPHANOL PRODRUGS AND PROCESSES FOR MAKING AND USING THEM | OPRM1, OPRK1, OPRD1 | OPRM1 1/4885OPRD1 3/4885OPRK1 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.