SCHEMBL22804106

SCHEMBL22804106

CC(C)(C)OC(=O)n1cc(C[C@@H](NC(=O)OCc2ccccc2)C(=O)O)c2ccccc21

nearest known ligand 0.55

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ ADAM17 P78536 1/20 0.53
▸ L3MBTL1 Q9Y468 1/20 0.53
▸ CCKAR P32238 3/20 0.51
▸ CCKBR P32239 3/20 0.51
▸ OPRD1 P41143 3/20 0.51
▸ MEN1 O00255 1/20 0.50
▸ RECQL P46063 1/20 0.50
▸ KMT2A Q03164 1/20 0.50
▸ ITGB3 P05106 2/20 0.47
▸ ITGA2B P08514 2/20 0.47
▸ SYK P43405 1/20 0.45
▸ PPARA Q07869 1/20 0.45
▸ ACE P12821 2/20 0.45
▸ EPHX1 P07099 1/20 0.44
▸ P2RX7 Q99572 2/20 0.43
▸ ACHE P22303 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17959465 1.00 ADAM17 (0.53) ADAM17L3MBTL1CCKARCCKBROPRD1
SCHEMBL29400895 1.00 ADAM17 (0.53) ADAM17L3MBTL1CCKARCCKBROPRD1
SCHEMBL17959463 1.00 ADAM17 (0.53) ADAM17L3MBTL1CCKARCCKBROPRD1
SCHEMBL29400289 1.00 ADAM17 (0.53) ADAM17L3MBTL1CCKARCCKBROPRD1
SCHEMBL14347099 0.93 CCKBR (0.57) ADAM17L3MBTL1CCKARCCKBROPRD1
SCHEMBL1258755 0.93 L3MBTL1 (0.51) ADAM17L3MBTL1CCKARCCKBROPRD1
SCHEMBL29398606 0.91 EPHX1 (0.49) ADAM17L3MBTL1CCKARCCKBROPRD1
SCHEMBL22804050 0.90 ADAM17 (0.58) ADAM17L3MBTL1CCKARCCKBROPRD1
SCHEMBL22804088 0.90 MEN1 (0.56) MEN1RECQLKMT2AITGB3ITGA2B
SCHEMBL22804099 0.90 MEN1 (0.56) MEN1RECQLKMT2AITGB3ITGA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3988538-A1 MODIFIED HYDROPHOBIC AUXILIARY MATERIAL, PREPARATION METHOD THEREFOR AND USE THEREOF Zhejiang Zhida Pharmaceutical Co., Ltd. (CN) 2022-04-27 — — EP claimed
US-20220111055-A1 MODIFIED HYDROPHOBIC EXCIPIENT AND PREPARATION METHOD THEREOF ZHEJIANG ZHIDA PHARMACEUTICAL CO., LTD. (CN) 2022-04-14 — — US claimed
WO-2020252713-A1 MODIFIED HYDROPHOBIC AUXILIARY MATERIAL, PREPARATION METHOD THEREFOR AND USE THEREOF 浙江智达药业有限公司 2020-12-24 — — WO claimed
US-12616676-B2 Preparation method and use of modified hydrophobic excipient ZHEJIANG ZHIDA PHARMACEUTICAL CO., LTD. (CN) 2026-05-05 — — US disclosed
EP-3988538-B1 MODIFIED HYDROPHOBIC AUXILIARY MATERIAL, PREPARATION METHOD THEREFOR AND USE THEREOF ZHEJIANG ZHIDA PHARMACEUTICAL CO LTD (CN) 2024-08-07 — — EP disclosed
EP-3988538-A1 MODIFIED HYDROPHOBIC AUXILIARY MATERIAL, PREPARATION METHOD THEREFOR AND USE THEREOF Zhejiang Zhida Pharmaceutical Co., Ltd. (CN) 2022-04-27 — — EP disclosed
US-20220111055-A1 MODIFIED HYDROPHOBIC EXCIPIENT AND PREPARATION METHOD THEREOF ZHEJIANG ZHIDA PHARMACEUTICAL CO., LTD. (CN) 2022-04-14 — — US disclosed
US-20220110909-A1 PREPARATION METHOD AND USE OF MODIFIED HYDROPHOBIC EXCIPIENT ZHEJIANG ZHIDA PHARMACEUTICAL CO., LTD. (CN) 2022-04-14 — — US disclosed
US-20220111056-A1 DRUG-LOADED EMULSION ZHEJIANG ZHIDA PHARMACEUTICAL CO., LTD. (CN) 2022-04-14 — — US disclosed
WO-2020252713-A1 MODIFIED HYDROPHOBIC AUXILIARY MATERIAL, PREPARATION METHOD THEREFOR AND USE THEREOF 浙江智达药业有限公司 2020-12-24 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12616676-B2 Preparation method and use of modified hydrophobic excipient CETP, LIPA, MTTP ADAM17 2068/4885L3MBTL1 3657/4885CCKAR 1467/4885
US-20220111056-A1 DRUG-LOADED EMULSION SLC43A1, SLC7A1, CETP ADAM17 3404/4885L3MBTL1 799/4885CCKAR 1894/4885
US-20220111055-A1 MODIFIED HYDROPHOBIC EXCIPIENT AND PREPARATION METHOD THEREOF CETP, SLC43A1, SLC27A1 ADAM17 2880/4885L3MBTL1 554/4885CCKAR 1150/4885
US-20220110909-A1 PREPARATION METHOD AND USE OF MODIFIED HYDROPHOBIC EXCIPIENT ABCG2, CYP51A1, HACD3 ADAM17 1796/4885L3MBTL1 3778/4885CCKAR 3960/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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