Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCEH1 | Q6PIU2 | 6/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PRNP | P04156 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | WDR5 | P61964 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2558131 | 0.78 | PKM (0.42) | PRNPRXFP1LMNAALDH1A1KEAP1 | |
| SCHEMBL2399724 | 0.74 | NCEH1 (0.49) | NCEH1POLBSMN1; SMN2NPC1RAB9A | |
| SCHEMBL592773 | 0.73 | EP300 (0.51) | KEAP1NFE2L2LDHA | |
| SCHEMBL16429292 | 0.72 | TSHR (0.33) | LMNAALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL22805939 | 0.72 | NCEH1 (0.31) | NCEH1 | |
| SCHEMBL206372 | 0.72 | MCL1 (0.58) | RAB9AMAPTKDM4E | |
| SCHEMBL28327542 | 0.71 | POLB (0.50) | NCEH1POLBSMN1; SMN2NPC1RAB9A | |
| SCHEMBL4154983 | 0.71 | TRPM8 (0.41) | MAPTRXFP1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL1648161 | 0.69 | PTGDR2 (0.36) | NCEH1POLBSMN1; SMN2MAPTPRNP | |
| SCHEMBL27698980 | 0.69 | RAB9A (0.39) | NCEH1POLBSMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3986865-A1 | NEW TRICYCLIC 5-HT2 ANTAGONISTS | AnaMar AB (SE) | 2022-04-27 | — | — | EP | disclosed |
| WO-2020254322-A1 | NEW TRICYCLIC 5-HT2 ANTAGONISTS | ANAMAR AB (SE) | 2020-12-24 | — | — | WO | disclosed |