Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLCO1B1 | Q9Y6L6 | 4/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.32 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.31 |
| ▸ | SELE | P16581 | 1/20 | 0.31 |
| ▸ | ABCC3 | O15438 | 2/20 | 0.31 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.31 |
| ▸ | SLCO1B3 | Q9NPD5 | 2/20 | 0.31 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.31 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29067845 | 0.89 | ABCB11 (0.38) | SLCO1B1ABCB11KDM4CNPC1RAB9A | |
| SCHEMBL23671228 | 0.88 | ABCB11 (0.35) | SLCO1B1ABCB11KDM4CNPC1RAB9A | |
| SCHEMBL21058017 | 0.85 | GABRA5 (0.40) | SLCO1B1KDM4CNPC1RAB9AMEN1 | |
| SCHEMBL30740368 | 0.84 | TGFBR1 (0.44) | SLCO1B1ABCB11KDM4CNPC1RAB9A | |
| SCHEMBL19715757 | 0.84 | SLCO1B1 (0.38) | SLCO1B1ABCB11KDM4CNPC1RAB9A | |
| SCHEMBL29411759 | 0.84 | SLCO1B1 (0.38) | SLCO1B1ABCB11KDM4CNPC1RAB9A | |
| SCHEMBL19728935 | 0.83 | ABCB11 (0.34) | SLCO1B1ABCB11KDM4CNPC1RAB9A | |
| SCHEMBL19715620 | 0.83 | DGAT1 (0.38) | SLCO1B1ABCB11KDM4CNPC1RAB9A | |
| SCHEMBL19715607 | 0.83 | SLCO1B1 (0.39) | SLCO1B1ABCB11KDM4CNPC1RAB9A | |
| SCHEMBL22463670 | 0.82 | KDM4C (0.38) | KDM4CNPC1RAB9ACYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12435057-B2 | Triazole carboxylic acids as LPA antagonists | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-10-07 | — | — | US | disclosed |
| US-20220235026-A1 | TRIAZOLE CARBOXYLIC ACIDS AS LPA ANTAGONISTS | BRISTOL-MYERS SQUIBB COMPANY | 2022-07-28 | — | — | US | disclosed |
| CN-114599648-A | Triazole carboxylic acids as LPA antagonists | 百时美施贵宝公司 | 2022-06-07 | — | — | CN | disclosed |
| EP-3986551-A1 | TRIAZOLE CARBOXYLIC ACIDS AS LPA ANTAGONISTS | Bristol-Myers Squibb Company (US) | 2022-04-27 | — | — | EP | disclosed |
| WO-2020257135-A1 | TRIAZOLE CARBOXYLIC ACIDS AS LPA ANTAGONISTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2020-12-24 | — | — | WO | disclosed |
| WO-2020257135-A1 | TRIAZOLE CARBOXYLIC ACIDS AS LPA ANTAGONISTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2020-12-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12435057-B2 | Triazole carboxylic acids as LPA antagonists | LPAR3, LPAR1, LPAR5 | SLCO1B1 824/4885ABCB11 1167/4885KDM4C 4179/4885 |
| US-20220235026-A1 | TRIAZOLE CARBOXYLIC ACIDS AS LPA ANTAGONISTS | LPAR3, LPAR1, LPAR5 | SLCO1B1 824/4885ABCB11 1167/4885KDM4C 4179/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.