Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 5/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | BCHE | P06276 | 2/20 | 0.57 |
| ▸ | ACHE | P22303 | 2/20 | 0.57 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA5A | P35218 | 1/20 | 0.54 |
| ▸ | CA7 | P43166 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.54 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14812262 | 0.89 | CRHBP (0.56) | SMN1; SMN2MAPTGAACA12CA1 | |
| SCHEMBL14812137 | 0.89 | CRHBP (0.56) | SMN1; SMN2MAPTGAACA12CA1 | |
| SCHEMBL5300654 | 0.83 | RAB9A (0.73) | EPHX2RAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL17365594 | 0.82 | POLB (0.66) | SMN1; SMN2ALDH1A1MAPTGAALMNA | |
| SCHEMBL7748974 | 0.82 | POLB (0.66) | SMN1; SMN2ALDH1A1MAPTGAALMNA | |
| SCHEMBL8009978 | 0.81 | CNR2 (0.56) | EPHX2ALDH1A1MAPTHPGDLMNA | |
| SCHEMBL5189919 | 0.81 | EPHX2 (0.65) | EPHX2RAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL11487355 | 0.80 | MAPT (0.72) | RAB9ASMN1; SMN2ALDH1A1MAPTNPC1 | |
| SCHEMBL14599718 | 0.80 | MAPT (0.72) | RAB9ASMN1; SMN2ALDH1A1MAPTNPC1 | |
| SCHEMBL1516167 | 0.79 | EPHX2 (1.00) | EPHX2RAB9ASMN1; SMN2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10870663-B2 | Compounds useful in HIV therapy | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2020-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10870663-B2 | Compounds useful in HIV therapy | CCR5, SLC11A2, CD4 | EPHX2 3059/4885RAB9A 1879/4885SMN1; SMN2 2433/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.