Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.50 |
| ▸ | NAAA | Q02083 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22813565 | 0.90 | KMT2A (0.52) | KMT2ANPC1TDP1NAAAALDH1A1 | |
| SCHEMBL19059202 | 0.84 | HTT (0.60) | KMT2AALDH1A1 | |
| SCHEMBL9425644 | 0.82 | ALOX5 (0.60) | KMT2ANPC1TDP1ALDH1A1 | |
| SCHEMBL7847132 | 0.79 | RAB9A (0.58) | NPC1ALDH1A1 | |
| SCHEMBL585819 | 0.79 | FFAR4 (0.60) | ALDH1A1 | |
| SCHEMBL16825165 | 0.78 | LMNA (0.54) | KMT2ANPC1ALDH1A1 | |
| SCHEMBL584916 | 0.77 | HTT (0.52) | ALDH1A1 | |
| SCHEMBL14892303 | 0.77 | HTT (0.54) | ALDH1A1 | |
| SCHEMBL10305162 | 0.77 | FKBP1A (0.76) | KMT2ANPC1TDP1NAAAALDH1A1 | |
| SCHEMBL13636214 | 0.77 | KMT2A (0.47) | KMT2AHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3253734-B1 | GLUCOSYLCERAMIDE SYNTHASE INHIBITORS AND THERAPEUTIC METHODS USING THE SAME | UNIV MICHIGAN REGENTS (US) | 2020-12-23 | — | — | EP | disclosed |