Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SUV39H2 | Q9H5I1 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 6/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | BPTF | Q12830 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.30 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23484653 | 0.82 | USP2 (0.38) | SUV39H2USP2CYP1A2CYP2D6HSD17B10 | |
| SCHEMBL22817132 | 0.76 | EBP (0.39) | BPTF | |
| SCHEMBL15945568 | 0.70 | LMNA (0.41) | SUV39H2HSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL612703 | 0.70 | LGMN (0.37) | SUV39H2USP2CYP1A2CYP2D6HSD17B10 | |
| SCHEMBL28984332 | 0.68 | DRD2 (0.51) | ALDH1A1MEN1KMT2ATSHRMAPK1 | |
| SCHEMBL10177533 | 0.68 | DPP4 (0.46) | CYP1A2CYP3A4CYP2C9CYP2C19MEN1 | |
| SCHEMBL13036989 | 0.68 | DPP4 (0.46) | CYP1A2CYP3A4CYP2C9CYP2C19MEN1 | |
| SCHEMBL12208682 | 0.67 | IKBKE (0.41) | SUV39H2CYP1A2CYP3A4CYP2C9ALDH1A1 | |
| SCHEMBL20010985 | 0.67 | HTR2C (0.47) | SUV39H2TSHRIKBKETBK1 | |
| SCHEMBL731260 | 0.67 | ALDH1A1 (0.41) | SUV39H2USP2HSD17B10ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020257487-A1 | GLYCOLATE OXIDASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2020-12-24 | — | — | WO | disclosed |