Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 10/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 10/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.37 |
| ▸ | AGXT | P21549 | 1/20 | 0.35 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.35 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL612703 | 0.84 | LGMN (0.37) | USP2HSD17B10ALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL22817138 | 0.82 | SUV39H2 (0.33) | USP2HSD17B10ALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL12208682 | 0.76 | IKBKE (0.41) | ALDH1A1CYP1A2CYP3A4MAPK1CYP2C9 | |
| SCHEMBL731260 | 0.76 | ALDH1A1 (0.41) | USP2HSD17B10ALDH1A1MAPK1TSHR | |
| SCHEMBL20010985 | 0.76 | HTR2C (0.47) | TSHRSUV39H2IKBKETBK1HTR7 | |
| SCHEMBL15945568 | 0.76 | LMNA (0.41) | HSD17B10ALDH1A1MAPK1TSHRSMN1; SMN2 | |
| SCHEMBL14403246 | 0.74 | TBK1 (0.43) | SUV39H2IKBKETBK1 | |
| SCHEMBL22816237 | 0.73 | LGMN (0.38) | USP2HSD17B10ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL13804695 | 0.73 | CLK4 (0.38) | SUV39H2IKBKETBK1 | |
| SCHEMBL22816721 | 0.73 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2KMT2ASUV39H2IKBKE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11384055-B2 | Glycolate oxidase inhibitors for the treatment of disease | BIOMARIN PHARMACEUTICAL INC. (US) | 2022-07-12 | — | — | US | disclosed |
| US-20210171474-A1 | GLYCOLATE OXIDASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2021-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11384055-B2 | Glycolate oxidase inhibitors for the treatment of disease | XDH, PNPO, AGXT | USP2 1874/4885HSD17B10 296/4885ALDH1A1 481/4885 |
| US-20210171474-A1 | GLYCOLATE OXIDASE INHIBITORS FOR THE TREATMENT OF DISEASE | XDH, PNPO, AGXT | USP2 1874/4885HSD17B10 296/4885ALDH1A1 481/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.