Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.71 |
| ▸ | MAPT | P10636 | 6/20 | 0.71 |
| ▸ | TP53 | P04637 | 5/20 | 0.71 |
| ▸ | NPC1 | O15118 | 1/20 | 0.71 |
| ▸ | RAB9A | P51151 | 1/20 | 0.71 |
| ▸ | HTT | P42858 | 5/20 | 0.70 |
| ▸ | LMNA | P02545 | 4/20 | 0.70 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.70 |
| ▸ | GAA | P10253 | 2/20 | 0.70 |
| ▸ | TSHR | P16473 | 2/20 | 0.70 |
| ▸ | CNR2 | P34972 | 1/20 | 0.70 |
| ▸ | MEN1 | O00255 | 2/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.70 |
| ▸ | HPGD | P15428 | 4/20 | 0.69 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.67 |
| ▸ | CASR | P41180 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8228786 | 0.86 | ALDH1A1 (0.67) | KDM4EALDH1A1SMN1; SMN2MAPTTP53 | |
| SCHEMBL10080422 | 0.85 | KDM4E (0.80) | KDM4EALDH1A1SMN1; SMN2MAPTTP53 | |
| SCHEMBL31267426 | 0.83 | KDM4E (0.72) | KDM4EALDH1A1SMN1; SMN2MAPTTP53 | |
| SCHEMBL30496676 | 0.82 | KDM4E (1.00) | KDM4EALDH1A1SMN1; SMN2MAPTTP53 | |
| SCHEMBL5582025 | 0.82 | ALDH1A1 (1.00) | KDM4EALDH1A1SMN1; SMN2MAPTTP53 | |
| SCHEMBL28141462 | 0.82 | KDM4E (0.75) | KDM4EALDH1A1SMN1; SMN2MAPTTP53 | |
| SCHEMBL10061943 | 0.80 | KDM4E (0.70) | KDM4EALDH1A1SMN1; SMN2MAPTTP53 | |
| SCHEMBL13784140 | 0.80 | HSD17B10 (0.58) | KDM4EALDH1A1SMN1; SMN2MAPTTP53 | |
| SCHEMBL10061946 | 0.80 | KDM4E (1.00) | KDM4EALDH1A1SMN1; SMN2MAPTTP53 | |
| SCHEMBL3431636 | 0.80 | ALDH1A1 (0.79) | KDM4EALDH1A1SMN1; SMN2MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11641857-B2 | Unusually potent ABA receptor pan-antagonists | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-05-09 | — | — | US | disclosed |
| US-11641857-B2 | Unusually potent ABA receptor pan-antagonists | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-05-09 | — | — | US | disclosed |
| US-20200397000-A1 | UNUSUALLY POTENT ABA RECEPTOR PAN-ANTAGONISTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-12-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200397000-A1 | UNUSUALLY POTENT ABA RECEPTOR PAN-ANTAGONISTS | AAK1, ATP5PO, BROX | KDM4E 3630/4885ALDH1A1 4006/4885SMN1; SMN2 4881/4885 |
| US-11641857-B2 | Unusually potent ABA receptor pan-antagonists | AAK1, ATP5PO, BROX | KDM4E 3630/4885ALDH1A1 4006/4885SMN1; SMN2 4881/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.