Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 1.00 |
| ▸ | HTT | P42858 | 5/20 | 1.00 |
| ▸ | LMNA | P02545 | 3/20 | 1.00 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 1.00 |
| ▸ | CNR2 | P34972 | 1/20 | 1.00 |
| ▸ | TP53 | P04637 | 6/20 | 0.92 |
| ▸ | MAPT | P10636 | 5/20 | 0.92 |
| ▸ | HPGD | P15428 | 3/20 | 0.92 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.92 |
| ▸ | GAA | P10253 | 3/20 | 0.84 |
| ▸ | NPC1 | O15118 | 1/20 | 0.73 |
| ▸ | RAB9A | P51151 | 1/20 | 0.73 |
| ▸ | TSHR | P16473 | 2/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.72 |
| ▸ | PDE6D | O43924 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10443668 | 0.96 | ALDH1A1 (0.92) | ALDH1A1KDM4ESMN1; SMN2HTTLMNA | |
| SCHEMBL8027362 | 0.89 | KDM4E (0.79) | ALDH1A1KDM4ESMN1; SMN2HTTLMNA | |
| SCHEMBL10443667 | 0.86 | ALDH1A1 (0.82) | ALDH1A1KDM4ESMN1; SMN2HTTLMNA | |
| SCHEMBL8022079 | 0.86 | KDM4E (0.76) | ALDH1A1KDM4ESMN1; SMN2HTTLMNA | |
| SCHEMBL14006013 | 0.86 | HTT (0.75) | ALDH1A1KDM4ESMN1; SMN2HTTLMNA | |
| SCHEMBL10080422 | 0.86 | KDM4E (0.80) | ALDH1A1KDM4ESMN1; SMN2HTTLMNA | |
| SCHEMBL8393562 | 0.86 | SMN1; SMN2 (0.73) | ALDH1A1KDM4ESMN1; SMN2HTTLMNA | |
| SCHEMBL5581775 | 0.85 | TP53 (0.91) | ALDH1A1KDM4ESMN1; SMN2HTTLMNA | |
| SCHEMBL9042664 | 0.84 | ALDH1A1 (0.71) | ALDH1A1KDM4ESMN1; SMN2HTTLMNA | |
| SCHEMBL10061946 | 0.84 | KDM4E (1.00) | ALDH1A1KDM4ESMN1; SMN2HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012108689-A2 | NOVEL COMPOUND HAVING SKIN-WHITENING, ANTI-OXIDIZING AND PPAR ACTIVITIES AND MEDICAL USE THEREFOR | 부산대학교 산학협력단 (KR) | 2012-08-16 | — | — | WO | claimed |
| US-20230295116-A1 | PROTEASOME ENHANCERS AND USES THEREOF | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY | 2023-09-21 | — | — | US | disclosed |
| US-20230295116-A1 | PROTEASOME ENHANCERS AND USES THEREOF | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY | 2023-09-21 | — | — | US | disclosed |
| CN-108997221-B | Method for synthesizing 1, 2-disubstituted benzimidazole compound by using 3-hydroxy-2-naphthoic acid and dichlorotitanocene | 陕西师范大学 | 2021-10-01 | — | — | CN | disclosed |
| CN-110845423-A | Preparation method of 1, 2-substituted benzimidazole compound | 井冈山大学 | 2020-02-28 | — | — | CN | disclosed |
| CN-108997221-A | The method that 3- hydroxy-2-naphthoic acid cooperates with cyclopentadienyl titanium dichloride synthesis 1,2- disubstituted benzenes and glyoxaline compound | 陕西师范大学 | 2018-12-14 | — | — | CN | disclosed |
| US-20150366776-A1 | NOVEL COMPOUND HAVING SKIN-WHITENING, ANTI-OXIDIZING AND PPAR ACTIVITIES AND MEDICAL USE THEREOF | PUSAN NAT UNIV IND COOP FOUND (KR) | 2015-12-24 | — | — | US | disclosed |
| US-20150366776-A1 | NOVEL COMPOUND HAVING SKIN-WHITENING, ANTI-OXIDIZING AND PPAR ACTIVITIES AND MEDICAL USE THEREOF | PUSAN NAT UNIV IND COOP FOUND (KR) | 2015-12-24 | — | — | US | disclosed |
| US-20150366776-A1 | NOVEL COMPOUND HAVING SKIN-WHITENING, ANTI-OXIDIZING AND PPAR ACTIVITIES AND MEDICAL USE THEREOF | PUSAN NAT UNIV IND COOP FOUND (KR) | 2015-12-24 | — | — | US | disclosed |
| US-9155690-B2 | Compound having skin-whitening, anti-oxidizing and PPAR activities and medical use thereof | PUSAN NATIONAL UNIVERSITY INDUSTRY-UNIVERSITY COOPERATION FOUNDATION (KR) | 2015-10-13 | — | — | US | disclosed |
| US-8889881-B2 | Compound having skin-whitening, anti-oxidizing and PPAR activities and medical use therefor | Pusan National University Industry —University Cooperation Foundation (KR) | 2014-11-18 | — | — | US | disclosed |
| US-8889881-B2 | Compound having skin-whitening, anti-oxidizing and PPAR activities and medical use therefor | Pusan National University Industry —University Cooperation Foundation (KR) | 2014-11-18 | — | — | US | disclosed |
| US-20140037564-A1 | NOVEL COMPOUND HAVING SKIN-WHITENING, ANTI-OXIDIZING AND PPAR ACTIVITIES AND MEDICAL USE THEREFOR | Pusan National University Indusrtyuniversity (KR) | 2014-02-06 | — | — | US | disclosed |
| US-20140037564-A1 | NOVEL COMPOUND HAVING SKIN-WHITENING, ANTI-OXIDIZING AND PPAR ACTIVITIES AND MEDICAL USE THEREFOR | Pusan National University Indusrtyuniversity (KR) | 2014-02-06 | — | — | US | disclosed |
| US-20140037564-A1 | NOVEL COMPOUND HAVING SKIN-WHITENING, ANTI-OXIDIZING AND PPAR ACTIVITIES AND MEDICAL USE THEREFOR | Pusan National University Indusrtyuniversity (KR) | 2014-02-06 | — | — | US | disclosed |
| WO-2012108689-A2 | NOVEL COMPOUND HAVING SKIN-WHITENING, ANTI-OXIDIZING AND PPAR ACTIVITIES AND MEDICAL USE THEREFOR | 부산대학교 산학협력단 (KR) | 2012-08-16 | — | — | WO | disclosed |
| US-7193088-B2 | Iridium complexes as light emitting materials and organic light emitting diode device | CHI MEI OPTOELECTRONICS (TW) | 2007-03-20 | — | — | US | disclosed |
| US-7193088-B2 | Iridium complexes as light emitting materials and organic light emitting diode device | CHI MEI OPTOELECTRONICS (TW) | 2007-03-20 | — | — | US | disclosed |
| US-7193088-B2 | Iridium complexes as light emitting materials and organic light emitting diode device | CHI MEI OPTOELECTRONICS (TW) | 2007-03-20 | — | — | US | disclosed |
| US-20050116626-A1 | Iridium complexes as light emitting materials and organic light emitting diode device | Innolux Corporation (TW) | 2005-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150366776-A1 | NOVEL COMPOUND HAVING SKIN-WHITENING, ANTI-OXIDIZING AND PPAR ACTIVITIES AND MEDICAL USE THEREOF | PPARG, PPARA, TYR | ALDH1A1 213/4885KDM4E 3430/4885SMN1; SMN2 3671/4885 |
| US-20140037564-A1 | NOVEL COMPOUND HAVING SKIN-WHITENING, ANTI-OXIDIZING AND PPAR ACTIVITIES AND MEDICAL USE THEREFOR | PPARG, PPARA, PPARD | ALDH1A1 186/4885KDM4E 3588/4885SMN1; SMN2 4087/4885 |
| US-20050116626-A1 | Iridium complexes as light emitting materials and organic light emitting diode device | ORC3, CRY1, ITGA1 | ALDH1A1 282/4885KDM4E 4039/4885SMN1; SMN2 4300/4885 |
| US-20230295116-A1 | PROTEASOME ENHANCERS AND USES THEREOF | PSME3, PSME4, ADRM1 | ALDH1A1 2806/4885KDM4E 839/4885SMN1; SMN2 126/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.