Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 2/20 | 0.34 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.34 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.34 |
| ▸ | PELI1 | Q96FA3 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1630764 | 0.85 | CHRNB2 (0.44) | CHRNB2CHRNB4CHRNA3CHRNA4PARP1 | |
| SCHEMBL2486077 | 0.85 | CHRNB2 (0.44) | CHRNB2CHRNB4CHRNA3CHRNA4PARP1 | |
| SCHEMBL1630761 | 0.85 | CHRNB2 (0.44) | CHRNB2CHRNB4CHRNA3CHRNA4PARP1 | |
| SCHEMBL15582912 | 0.77 | — | — | |
| SCHEMBL20107561 | 0.74 | — | — | |
| SCHEMBL178479 | 0.74 | — | — | |
| SCHEMBL277483 | 0.74 | — | — | |
| SCHEMBL15449450 | 0.74 | — | — | |
| SCHEMBL2166225 | 0.74 | — | — | |
| SCHEMBL18292204 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200399634-A1 | DNA-TEMPLATED MACROCYCLE LIBRARY | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2020-12-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200399634-A1 | DNA-TEMPLATED MACROCYCLE LIBRARY | IDE, IAPP, POLRMT | CHRNB2 4779/4885CHRNB4 4752/4885CHRNA3 4728/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.