SCHEMBL22824136

SCHEMBL22824136

Cc1cc(-c2cc(C)c(-c3ccc(C(=O)O)cc3)cc2C)c(C)cc1-c1ccc(C(=O)O)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXRA P19793 7/20 0.57
RXRB P28702 4/20 0.57
RARB P10826 3/20 0.54
RARG P13631 1/20 0.53
ALDH1A1 P00352 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
ADH5 P11766 1/20 0.50
TP53 P04637 1/20 0.50
TSHR P16473 1/20 0.50
HSD17B1 P14061 1/20 0.49
RARA P10276 1/20 0.48
MAP4K4 O95819 1/20 0.47
GRIK1 P39086 1/20 0.47
GRIA1 P42261 1/20 0.47
GRIA2 P42262 1/20 0.47
GRIA3 P42263 1/20 0.47
GRIA4 P48058 1/20 0.47
RXRG P48443 1/20 0.47
SRD5A2 P31213 1/20 0.47
BCL2L1 Q07817 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16749653 0.98 RXRA (0.59) RXRARXRBRARBRARGALDH1A1
SCHEMBL2951077 0.94 RXRA (0.55) RXRARXRBRARBRARGALDH1A1
SCHEMBL25597224 0.93 HSD17B1 (0.60) RXRARXRBRARBRARGALDH1A1
SCHEMBL26878926 0.89 RARB (0.52) RXRARXRBRARBRARGALDH1A1
SCHEMBL26878712 0.88 EGFR (0.54) RXRARXRBRARBRARGALDH1A1
SCHEMBL21260968 0.88 RARB (0.46) RXRARXRBRARBRARGALDH1A1
SCHEMBL22859342 0.88 RARB (0.46) RXRARXRBRARBRARGALDH1A1
SCHEMBL25125811 0.87 SRD5A2 (0.55) RXRARXRBRARBRARGALDH1A1
SCHEMBL31611775 0.87 RXRA (0.49) RXRARXRBRARBRARGALDH1A1
SCHEMBL4603074 0.86 GRIK1 (0.62) RXRARXRBRARBRARGALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250177965-A1 HETEROGENEOUS CATALYSTS AND METHODS MAKING AND USING THEREOF THE UNIVERSITY OF HONG KONG (CN) 2025-06-05 US claimed
US-20250177965-A1 HETEROGENEOUS CATALYSTS AND METHODS MAKING AND USING THEREOF THE UNIVERSITY OF HONG KONG (CN) 2025-06-05 US disclosed
US-20230381740-A1 MULTIVARIATE METAL-ORGANIC FRAMEWORKS FOR FINE-TUNING LIGHT EMISSION UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. 2023-11-30 US disclosed
US-20230381740-A1 MULTIVARIATE METAL-ORGANIC FRAMEWORKS FOR FINE-TUNING LIGHT EMISSION UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. 2023-11-30 US disclosed
US-11679372-B2 Multivariate metal-organic frameworks for fine-tuning light emission UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (US) 2023-06-20 US disclosed
US-11679372-B2 Multivariate metal-organic frameworks for fine-tuning light emission UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (US) 2023-06-20 US disclosed
US-20200398250-A1 MULTIVARIATE METAL-ORGANIC FRAMEWORKS FOR FINE-TUNING LIGHT EMISSION UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. 2020-12-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11679372-B2 Multivariate metal-organic frameworks for fine-tuning light emission ILF2, MORF4L1, YTHDF2 RXRA 1520/4885RXRB 1657/4885RARB 1105/4885
US-20200398250-A1 MULTIVARIATE METAL-ORGANIC FRAMEWORKS FOR FINE-TUNING LIGHT EMISSION ILF2, MORF4L1, YTHDF2 RXRA 1520/4885RXRB 1657/4885RARB 1105/4885
US-20230381740-A1 MULTIVARIATE METAL-ORGANIC FRAMEWORKS FOR FINE-TUNING LIGHT EMISSION ILF2, MORF4L1, YTHDF2 RXRA 1520/4885RXRB 1657/4885RARB 1105/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.