Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 3/20 | 0.46 |
| ▸ | RXRA | P19793 | 7/20 | 0.46 |
| ▸ | RXRB | P28702 | 4/20 | 0.46 |
| ▸ | RARG | P13631 | 1/20 | 0.45 |
| ▸ | ADH5 | P11766 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | RARA | P10276 | 1/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.40 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.40 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.40 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.40 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 2/20 | 0.40 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21260968 | 1.00 | RARB (0.46) | RARBRXRARXRBRARGADH5 | |
| SCHEMBL22824136 | 0.88 | RXRA (0.57) | RARBRXRARXRBRARGADH5 | |
| SCHEMBL25634115 | 0.87 | RARB (0.43) | RARBRXRARXRBRARGADH5 | |
| SCHEMBL16749653 | 0.86 | RXRA (0.59) | RARBRXRARXRBRARGADH5 | |
| SCHEMBL15521776 | 0.84 | TP53 (0.50) | RXRARXRBMAP4K4RXRGTP53 | |
| SCHEMBL29434901 | 0.84 | TP53 (0.50) | RXRARXRBMAP4K4RXRGTP53 | |
| SCHEMBL29434900 | 0.84 | TP53 (0.50) | RXRARXRBMAP4K4RXRGTP53 | |
| SCHEMBL18746226 | 0.83 | ALDH1A1 (0.59) | RXRARXRBALDH1A1SMN1; SMN2MAP4K4 | |
| SCHEMBL2951077 | 0.83 | RXRA (0.55) | RARBRXRARXRBRARGADH5 | |
| SCHEMBL25597224 | 0.81 | HSD17B1 (0.60) | RARBRXRARXRBRARGADH5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230194165-A1 | RADIOFREQUENCY HEATING OF WOOD USING A THREE-ELECTRODE SYSTEM HAVING A WINGED CENTRAL ELECTRODE | RF KILN TECH LIMITED (CA) | 2023-06-22 | — | — | US | disclosed |
| US-11666637-B2 | Insulin-loaded metal-organic frameworks | NORTHWESTERN UNIVERSITY (US) | 2023-06-06 | — | — | US | disclosed |
| US-20210000924-A1 | INSULIN-LOADED METAL-ORGANIC FRAMEWORKS | NORTHWESTERN UNIVERSITY | 2021-01-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11666637-B2 | Insulin-loaded metal-organic frameworks | IAPP, IGFBP4, IGFBP1 | RARB 2732/4885RXRA 3489/4885RXRB 3363/4885 |
| US-20210000924-A1 | INSULIN-LOADED METAL-ORGANIC FRAMEWORKS | IAPP, IGFBP4, IGFBP1 | RARB 2732/4885RXRA 3489/4885RXRB 3363/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.