Sugi Predict

Sugi Predict / Compounds / SCHEMBL619907

SCHEMBL619907

SCHEMBL619907

COC(=O)c1c(O)cccc1F

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CA12 O43570 4/20 0.77
▸ CA1 P00915 4/20 0.77
▸ CA2 P00918 4/20 0.77
▸ CA7 P43166 4/20 0.77
▸ CA9 Q16790 4/20 0.77
▸ CA14 Q9ULX7 4/20 0.77
▸ LMNA P02545 2/20 0.50
▸ TSHR P16473 1/20 0.50
▸ CES2 O00748 1/20 0.48
▸ CES1 P23141 1/20 0.48
▸ THRB P10828 1/20 0.47
▸ KDM4E B2RXH2 2/20 0.46
▸ HSD17B10 Q99714 1/20 0.46
▸ BDKRB1 P46663 2/20 0.45
▸ RAB9A P51151 1/20 0.44
▸ KMT2A Q03164 4/20 0.44
▸ POLB P06746 2/20 0.43
▸ MEN1 O00255 2/20 0.43
▸ GAA P10253 1/20 0.42
▸ NFKB1 P19838 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1070351 0.88 CA12 (0.61) CA12CA1CA2CA7CA9
SCHEMBL1519936 0.88 CA12 (1.00) CA12CA1CA2CA7CA9
SCHEMBL28869955 0.85 CA12 (0.56) CA12CA1CA2CA7CA9
SCHEMBL8479501 0.84 CA1 (0.59) CA12CA1CA2CA7CA9
SCHEMBL30632216 0.81 CA12 (0.53) CA12CA1CA2CA7CA9
SCHEMBL30432593 0.81 CA12 (0.53) CA12CA1CA2CA7CA9
SCHEMBL621753 0.81 CA12 (0.53) CA12CA1CA2CA7CA9
SCHEMBL8056782 0.81 CA12 (0.53) CA12CA1CA2CA7CA9
SCHEMBL20899341 0.80 CA12 (0.79) CA12CA1CA2CA7CA9
SCHEMBL17374999 0.80 CA12 (0.48) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 134 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118904215-A Polymerization system and polymerization method of 2-hydroxy-6-fluorobenzoic acid methyl ester 江苏万隆化学有限公司 2024-11-08 — — CN claimed
US-20240115470-A1 METHYL-FLUORO-HYDROXYBENZOATES IN CONSUMER PRODUCTS SA, GIVAUDAN (CH) 2024-04-11 — — US claimed
CN-117796401-A Preparation process of 2-hydroxy-6-fluorobenzoic acid methyl ester-containing intermediate antibacterial agent 江苏万隆化学有限公司 2024-04-02 — — CN claimed
EP-4259082-A1 METHYL-FLUORO-HYDROXYBENZOATES IN CONSUMER PRODUCTS Givaudan SA (CH) 2023-10-18 — — EP claimed
WO-2022122836-A1 METHYL-FLUORO-HYDROXYBENZOATES IN CONSUMER PRODUCTS GIVAUDAN SA (CH) 2022-06-16 — — WO claimed
US-20260055062-A1 HETEROCYCLIC INHIBITORS OF MCT4 Vettore, LLC 2026-02-26 — — US disclosed
US-20250333406-A1 SULFONYL CYCLIC DERIVATIVES, AND COMPOSITIONS AND METHODS THEREOF LYSOWAY THERAPEUTICS INC (US) 2025-10-30 — — US disclosed
US-12398097-B2 WDR5-MYC inhibitors VANDERBILT UNIVERSITY (US) 2025-08-26 — — US disclosed
WO-2025061035-A1 BRM SELECTIVE DEGRADATION AGENT COMPOUND AND USE THEREOF 南京再明医药有限公司 2025-03-27 — — WO disclosed
CN-118904215-A Polymerization system and polymerization method of 2-hydroxy-6-fluorobenzoic acid methyl ester 江苏万隆化学有限公司 2024-11-08 — — CN disclosed
CN-118904215-A Polymerization system and polymerization method of 2-hydroxy-6-fluorobenzoic acid methyl ester 江苏万隆化学有限公司 2024-11-08 — — CN disclosed
CN-118904215-A Polymerization system and polymerization method of 2-hydroxy-6-fluorobenzoic acid methyl ester 江苏万隆化学有限公司 2024-11-08 — — CN disclosed
WO-2005066143-A2 BENZO[D]ISOXAZOL-3-OL DAAO INHIBITORS SEPRACOR INC. (US) 2005-07-21 — — WO disclosed
US-20050143434-A1 Benzo[d]isoxazol-3-ol DAAO inhibitors SEPRACOR INC. (US) 2005-06-30 — — US disclosed
WO-2005010006-A1 SUBSTITUTED FUROCHROMENE COMPOUNDS OF ANTIINFLAMMATORY ACTION PLIVA-ISTRAZIVACKI INSTITUT D.O.O. (HR) 2005-02-03 — — WO disclosed
US-20040209932-A1 1,3-substitued cycloalkyl derivatives having acidic, mostly heterocyclic groups; processes for their preparation and their use as pharmaceuticals AVENTIS PHARMA DEUTSCHLAND GMBH (DE) 2004-10-21 — — US disclosed
EP-0249708-B1 2-PHENOXYPYRIMIDINE DERIVATIVE AND HERBICIDAL COMPOSITIONS KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1992-03-11 — — EP disclosed
US-4985066-A 2-phenoxypyrimidine derivative and herbicidal composition KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1991-01-15 — — US disclosed
US-4900352-A 2-Phenoxypyimidine derivative and herbicidal composition KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1990-02-13 — — US disclosed
EP-0249708-A1 2-Phenoxypyrimidine derivative and herbicidal compositions KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1987-12-23 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050143434-A1 Benzo[d]isoxazol-3-ol DAAO inhibitors DDO, DAO, CACNA1S CA12 981/4885CA1 25/4885CA2 110/4885
US-20040209932-A1 1,3-substitued cycloalkyl derivatives having acidic, mostly heterocyclic groups; processes for their preparation and their use as pharmaceuticals GPR119, PC, CPT1A CA12 3030/4885CA1 3407/4885CA2 1587/4885
US-20240115470-A1 METHYL-FLUORO-HYDROXYBENZOATES IN CONSUMER PRODUCTS KDM5B, FOSB, KDM2B CA12 2279/4885CA1 3577/4885CA2 2648/4885
US-20250333406-A1 SULFONYL CYCLIC DERIVATIVES, AND COMPOSITIONS AND METHODS THEREOF STOML2, ATP2A3, ATP2A1 CA12 3436/4885CA1 2863/4885CA2 304/4885
US-12398097-B2 WDR5-MYC inhibitors MYC, WDR5, MYCBP CA12 4808/4885CA1 4853/4885CA2 4637/4885
US-20260055062-A1 HETEROCYCLIC INHIBITORS OF MCT4 SLC16A1, SLC16A3, SLC16A7 CA12 3279/4885CA1 3982/4885CA2 1174/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.