SCHEMBL22832292

SCHEMBL22832292

O=C(F)c1ccc(C(=O)c2ccc(C(=O)F)cc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRD5A2 P31213 6/20 0.55
LMNA P02545 3/20 0.55
MAPT P10636 3/20 0.55
HPGD P15428 2/20 0.55
ESR1 P03372 1/20 0.55
ESR2 Q92731 1/20 0.55
PKM P14618 1/20 0.55
HTT P42858 1/20 0.55
ALDH1A1 P00352 3/20 0.52
LTA4H P09960 1/20 0.46
MAPK1 P28482 1/20 0.44
ADRA2A P08913 1/20 0.42
ADRA2B P18089 1/20 0.42
ADRA2C P18825 1/20 0.42
ATM Q13315 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
MEN1 O00255 1/20 0.41
RAB9A P51151 1/20 0.41
KMT2A Q03164 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL102601 0.90 TSHR (0.47) SRD5A2LMNAMAPTHPGDESR1
SCHEMBL12212918 0.81 BCL2L1 (0.50) LMNAMAPTL3MBTL1MEN1RAB9A
SCHEMBL15256267 0.79 TSHR (0.71) SRD5A2ALDH1A1
SCHEMBL8023301 0.79 CES2 (0.65) MAPTLTA4HMEN1RAB9AKMT2A
SCHEMBL23391017 0.77 TPMT (0.59)
SCHEMBL8340738 0.77 ALDH1A1 (0.62) SRD5A2LMNAMAPTHPGDPKM
SCHEMBL23390994 0.77 LMNA (0.48) LMNAMAPTHPGDPKMHTT
SCHEMBL22386370 0.77 CES2 (0.62) LMNAMAPTHPGDALDH1A1MAPK1
SCHEMBL9834776 0.77 CES2 (0.62) SRD5A2LMNAMAPTHPGDALDH1A1
SCHEMBL23417802 0.77 MAPT (0.54) LMNAMAPTHPGDALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111836849-B Process for producing fibers, films and moldings of polybenzazole polymer (P) 巴斯夫欧洲公司 2023-04-07 CN disclosed
US-20200407508-A1 METHOD FOR PRODUCING FIBERS, FILMS AND MOLDINGS OF A POLYBENZAZOLE POLYMER (P) BASF SE (DE) 2020-12-31 US disclosed
CN-111836849-A Process for producing fibers, films and moldings of polybenzazole polymer (P) 巴斯夫欧洲公司 2020-10-27 CN disclosed