Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.62 |
| ▸ | CES2 | O00748 | 3/20 | 0.62 |
| ▸ | CES1 | P23141 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.54 |
| ▸ | ATM | Q13315 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.54 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | GSK3B | P49841 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL102601 | 0.85 | TSHR (0.47) | ALDH1A1CES2CES1LMNAHTT | |
| SCHEMBL4209872 | 0.79 | CES2 (0.71) | ALDH1A1CES2CES1LMNASMN1; SMN2 | |
| SCHEMBL23417802 | 0.78 | MAPT (0.54) | ALDH1A1LMNASMN1; SMN2NPSR1TDP1 | |
| SCHEMBL20118491 | 0.77 | ALDH1A1 (0.52) | ALDH1A1CES2CES1LMNASMN1; SMN2 | |
| SCHEMBL167254 | 0.77 | CES2 (1.00) | ALDH1A1CES2CES1LMNASMN1; SMN2 | |
| SCHEMBL822185 | 0.77 | ALDH1A1 (1.00) | ALDH1A1CES2CES1LMNASMN1; SMN2 | |
| SCHEMBL52200 | 0.77 | ALDH1A1 (1.00) | ALDH1A1CES2CES1LMNASMN1; SMN2 | |
| SCHEMBL12212918 | 0.77 | BCL2L1 (0.50) | CES2CES1LMNASMN1; SMN2KMT2A | |
| SCHEMBL22832292 | 0.77 | SRD5A2 (0.55) | ALDH1A1LMNAHTTTDP1KMT2A | |
| SCHEMBL17288381 | 0.77 | ALDH1A1 (0.52) | ALDH1A1CES2CES1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110698404-A | Preparation method of high-purity celecoxib | 安徽恒星制药有限公司 | 2020-01-17 | — | — | CN | claimed |
| EP-4707263-A1 | FLUORINATING AGENT AND FLUORINATION METHOD | Daikin Industries, Ltd. (JP) | 2026-03-11 | — | — | EP | disclosed |
| US-20240017996-A1 | FLUORINATION PROCESSES | UNIVERSITY COLLEGE LONDON (GB) | 2024-01-18 | — | — | US | disclosed |
| US-20230339829-A1 | FLUORINATION PROCESSES | UNIVERSITY COLLEGE LONDON (GB) | 2023-10-26 | — | — | US | disclosed |
| EP-3560910-B1 | METHOD FOR MANUFACTURING DIFLUOROMETHYLENE COMPOUND | DAIKIN IND LTD (JP) | 2023-03-29 | — | — | EP | disclosed |
| CN-110114334-B | Method for producing difluoromethylene compound | 大金工业株式会社 | 2022-06-17 | — | — | CN | disclosed |
| CN-110698404-A | Preparation method of high-purity celecoxib | 安徽恒星制药有限公司 | 2020-01-17 | — | — | CN | disclosed |
| EP-2445909-B1 | DERIVATIVES OF 6,7-DIHYDRO-5H-IMIDAZO[1,2-a]IMIDAZOLE-3-CARBOXYLIC ACID AMIDES | BOEHRINGER INGELHEIM INT (DE) | 2013-11-13 | — | — | EP | disclosed |
| EP-2308854-A1 | 2,3,6-trisubstituted-4-pyrimidone derivatives | Sanofi-Aventis (FR) | 2011-04-13 | — | — | EP | disclosed |
| EP-2305651-A1 | 2,3,6-trisubstituted-4-pyrimidone derivatives | Mitsubishi Tanabe Pharma Corporation (JP) | 2011-04-06 | — | — | EP | disclosed |
| WO-2004085408-A1 | 2, 3, 6-TRISUBSTITUTED-4-PYRIMIDONE DERIVATIVES | MITSUBISHI PHARMA CORPORATION (JP) | 2004-10-07 | — | — | WO | disclosed |
| EP-0847992-B1 | Benzamide derivatives, useful as cell differentiation inducers | SCHERING AG (DE) | 2004-06-23 | — | — | EP | disclosed |
| US-4555370-A | CYANTATION OF ACYL. FLUORIDE | BAYER AKTIENGESELLSCHAFT (DE) | 1985-11-26 | — | — | US | disclosed |
| EP-0038987-B1 | PROCESS FOR PREPARING ACYL CYANIDES | BAYER AG (DE) | 1983-06-08 | — | — | EP | disclosed |
| EP-0038987-A1 | Process for preparing acyl cyanides | BAYER AG (DE) | 1981-11-04 | — | — | EP | disclosed |
| EP-0018481-A1 | Process for producing alpha, alpha, alpha-trifluoro-o-toluic fluoride | NIHON NOHYAKU CO., LTD. (JP) | 1980-11-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230339829-A1 | FLUORINATION PROCESSES | PPIP5K2, PFAS, ARFGEF1 | ALDH1A1 3448/4885CES2 1518/4885CES1 3615/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.