Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB1 | P20618 | 2/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | RGS12 | O14924 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16654263 | 0.73 | — | — | |
| SCHEMBL11838294 | 0.72 | FPR2 (0.41) | KEAP1NFE2L2CYP2D6KMT2AALDH1A1 | |
| SCHEMBL8770339 | 0.71 | L3MBTL1 (0.40) | PSMB5KDM4ECYP3A4PKMTSHR | |
| SCHEMBL1724268 | 0.69 | MAPT (0.40) | PSMB1PSMB5KDM4ECYP3A4CYP2C9 | |
| SCHEMBL8709695 | 0.68 | NPC1 (0.34) | ALDH1A1LMNAPOLBMAPTNPSR1 | |
| SCHEMBL8609402 | 0.68 | SLC6A2 (0.45) | CYP3A4TSHRCYP2C19SLC6A4 | |
| SCHEMBL10610999 | 0.67 | L3MBTL1 (0.38) | KDM4EHSD17B10ALDH1A1LMNAPOLB | |
| SCHEMBL11389897 | 0.67 | CRBN (0.46) | PKMALDH1A1LMNA | |
| SCHEMBL31119353 | 0.66 | PSMB1 (0.31) | PSMB1PSMB5TSHRPOLBNPSR1 | |
| SCHEMBL3530061 | 0.65 | CYP1A2 (0.45) | TSHRALOX12HSD17B10KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3989921-A1 | SYNERGISTIC ANTI-INFLAMMATORY COMPOSITIONS | The Procter & Gamble Company (US) | 2022-05-04 | — | — | EP | claimed |
| WO-2020264577-A1 | SYNERGISTIC ANTI-INFLAMMATORY COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 2020-12-30 | — | — | WO | claimed |