⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8709695 | 0.76 | NPC1 (0.34) | — | |
| SCHEMBL8770339 | 0.74 | L3MBTL1 (0.40) | — | |
| SCHEMBL3530061 | 0.73 | CYP1A2 (0.45) | — | |
| SCHEMBL22836716 | 0.73 | PSMB1 (0.38) | — | |
| SCHEMBL22112809 | 0.71 | — | — | |
| SCHEMBL10610999 | 0.70 | L3MBTL1 (0.38) | — | |
| SCHEMBL31119353 | 0.69 | PSMB1 (0.31) | — | |
| SCHEMBL20598570 | 0.69 | CDC25A (0.34) | — | |
| SCHEMBL21475936 | 0.68 | PKM (0.35) | — | |
| SCHEMBL2465330 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3057586-A1 | BROMODOMAIN INHIBITORS | Celgene Quanticel Research, Inc. (US) | 2016-08-24 | — | — | EP | claimed |
| WO-2015058160-A1 | BROMODOMAIN INHIBITORS | Quanticel Pharmaceuticals, Inc. (US) | 2015-04-23 | — | — | WO | claimed |
| US-20240182490-A1 | BROMODOMAIN INHIBITORS | CELGENE QUANTICEL RESEARCH, INC. (US) | 2024-06-06 | — | — | US | disclosed |
| WO-2024107746-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES (US) | 2024-05-23 | — | — | WO | disclosed |
| US-20220315601-A1 | BROMODOMAIN INHIBITORS | CELGENE QUANTICEL RESEARCH, INC. (US) | 2022-10-06 | — | — | US | disclosed |
| CN-108137539-A | SUBSTITUTED BENZIMIDAZOLES, THEIR PREPARATION AND THEIR USE AS PHARMACEUTICALS | 尼奥迈德研究所 | 2018-06-08 | — | — | CN | disclosed |