Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 5/20 | 0.37 |
| ▸ | CA1 | P00915 | 3/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ESRRG | P62508 | 1/20 | 0.33 |
| ▸ | FLT1 | P17948 | 1/20 | 0.33 |
| ▸ | FLT4 | P35916 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.32 |
| ▸ | PARP4 | Q9UKK3 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.32 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.32 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.32 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20760154 | 0.89 | CA2 (0.35) | CA2CA1CA9CA12CA14 | |
| SCHEMBL22519836 | 0.89 | EPHX2 (0.37) | CA2CA1CA9CA12CA14 | |
| SCHEMBL23797104 | 0.84 | SMN1; SMN2 (0.43) | CA2CA1CA9CA12CA14 | |
| SCHEMBL21585329 | 0.77 | CA2 (0.37) | CA2CA1CA9CA12CA14 | |
| SCHEMBL24311856 | 0.73 | SMN1; SMN2 (0.44) | CA2CA1KDM4EKMT2AALDH1A1 | |
| SCHEMBL21504945 | 0.73 | CA2 (0.42) | CA2CA1CA9CA12CA14 | |
| SCHEMBL21504863 | 0.72 | SMN1; SMN2 (0.46) | CA2CA1KDM4EKMT2AALDH1A1 | |
| SCHEMBL25808865 | 0.72 | — | — | |
| SCHEMBL21338941 | 0.72 | — | — | |
| SCHEMBL20623069 | 0.70 | KEAP1 (0.39) | CA2CA1CA9CA12KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220386606-A1 | SPECIFICALLY SUBSTITUTED 3-PHENYL-5-SPIROCYCLOPENTYL-3-PYRROLIN-2-ONES AND THEIR USE AS HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2022-12-08 | — | — | US | disclosed |
| US-20210137117-A1 | HERBICIDAL MIXTURES | FMC CORPORATION | 2021-05-13 | — | — | US | disclosed |
| US-20200404914-A1 | HERBICIDALLY ACTIVE BICYCLIC BENZAMIDES | BAYER AG (DE) | 2020-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220386606-A1 | SPECIFICALLY SUBSTITUTED 3-PHENYL-5-SPIROCYCLOPENTYL-3-PYRROLIN-2-ONES AND THEIR USE AS HERBICIDES | DDT, HPD, AGPS | CA2 526/4885CA1 2761/4885CA9 1388/4885 |
| US-20210137117-A1 | HERBICIDAL MIXTURES | DDT, MTX2, ATL3 | CA2 75/4885CA1 773/4885CA9 546/4885 |
| US-20200404914-A1 | HERBICIDALLY ACTIVE BICYCLIC BENZAMIDES | CBR3, CBR1, AOX1 | CA2 226/4885CA1 442/4885CA9 753/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.