Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.32 |
| ▸ | AHR | P35869 | 1/20 | 0.31 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.31 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19389281 | 0.75 | PLA2G10 (0.31) | PLA2G2APLA2G4APLA2G10 | |
| SCHEMBL17716012 | 0.75 | GPR3 (0.50) | MAOAHSP90AA1HSP90AB1SMN1; SMN2KDM4E | |
| SCHEMBL25765635 | 0.75 | MEN1 (0.38) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL22989918 | 0.73 | PLA2G2A (0.36) | MAOAHSP90AA1HSP90AB1SMN1; SMN2KDM4E | |
| SCHEMBL20071932 | 0.71 | L3MBTL1 (0.36) | MAOAHSP90AA1HSP90AB1SMN1; SMN2KDM4E | |
| SCHEMBL22926738 | 0.71 | MAOA (0.39) | MAOASMN1; SMN2KDM4EMEN1NPC1 | |
| SCHEMBL22926734 | 0.71 | MAOA (0.36) | MAOASMN1; SMN2KDM4EMEN1NPC1 | |
| SCHEMBL24307736 | 0.70 | AHR (0.31) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL20071931 | 0.70 | HSP90AA1 (0.37) | MAOAHSP90AA1HSP90AB1SMN1; SMN2KDM4E | |
| SCHEMBL23131539 | 0.70 | PLA2G2A (0.35) | MAOAHSP90AA1HSP90AB1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210005821-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2021-01-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210005821-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | L1CAM, EFNA1, EPCAM | MAOA 582/4885HSP90AA1 4019/4885HSP90AB1 4428/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.