SCHEMBL22862364

SCHEMBL22862364

OCCc1ccc(C#Cc2ccc(COc3ccc(C#Cc4ccc(CCO)cc4)cc3)cc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ LTA4H P09960 1/20 0.57
▸ EPHX2 P34913 1/20 0.57
▸ FFAR1 O14842 5/20 0.49
▸ CYP4F2 P78329 1/20 0.49
▸ CYP4A11 Q02928 1/20 0.49
▸ FFAR4 Q5NUL3 2/20 0.47
▸ APP P05067 2/20 0.47
▸ CA2 P00918 1/20 0.47
▸ PTPN1 P18031 1/20 0.47
▸ PTPN6 P29350 1/20 0.47
▸ PTPN11 Q06124 1/20 0.47
▸ MAOB P27338 4/20 0.46
▸ PARP10 Q53GL7 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5700 0.83 LTA4H (0.80) LTA4HEPHX2FFAR1CYP4F2CYP4A11
SCHEMBL22862360 0.82 CA2 (0.54) FFAR1CYP4F2CYP4A11FFAR4CA2
SCHEMBL966309 0.81 MAOB (0.69) LTA4HEPHX2APPMAOB
SCHEMBL9121493 0.81 FFAR1 (0.66) LTA4HEPHX2FFAR1APPMAOB
SCHEMBL9125234 0.81 MAOB (0.60) LTA4HEPHX2FFAR1CYP4F2CYP4A11
SCHEMBL6029 0.81 CYP4F2 (0.71) LTA4HEPHX2FFAR1CYP4F2CYP4A11
Alcohol SCHEMBL5852437 0.79 LTA4H (0.73) LTA4HEPHX2FFAR1CYP4F2CYP4A11
SCHEMBL18002747 0.77 MAOB (0.69) LTA4HEPHX2FFAR1FFAR4PTPN1
SCHEMBL14786201 0.76 MAOB (0.71) LTA4HEPHX2FFAR1CA2PTPN1
SCHEMBL24802691 0.76 ACACB (0.51) FFAR1FFAR4PTPN1PTPN6PTPN11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210149098-A1 OPTICAL ELEMENT, METHOD FOR FORMING PHOTO-ALIGNMENT PATTERN, AND METHOD FOR MANUFACTURING OPTICAL ELEMENT FUJIFILM CORPORATION (JP) 2021-05-20 — — US disclosed
US-20210002556-A1 COMPOUND, COMPOSITION, CURED OBJECT, OPTICALLY ANISOTROPIC BODY, AND REFLECTIVE FILM FUJIFILM CORPORATION (JP) 2021-01-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210002556-A1 COMPOUND, COMPOSITION, CURED OBJECT, OPTICALLY ANISOTROPIC BODY, AND REFLECTIVE FILM MKI67, RB1, FLNA LTA4H 318/4885EPHX2 1506/4885FFAR1 315/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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