Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.71 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.71 |
| ▸ | LTA4H | P09960 | 1/20 | 0.71 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.71 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.66 |
| ▸ | APP | P05067 | 1/20 | 0.60 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | BCHE | P06276 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5700 | 0.94 | LTA4H (0.80) | CYP4F2CYP4A11LTA4HEPHX2FFAR1 | |
| Alcohol SCHEMBL5852437 | 0.89 | LTA4H (0.73) | CYP4F2CYP4A11LTA4HEPHX2FFAR1 | |
| SCHEMBL850999 | 0.85 | APP (0.78) | LTA4HEPHX2FFAR1APPLMNA | |
| SCHEMBL24041843 | 0.84 | ALDH1A1 (0.63) | CYP4F2CYP4A11LTA4HEPHX2FFAR1 | |
| SCHEMBL5400014 | 0.83 | APP (0.64) | CYP4F2CYP4A11LTA4HEPHX2FFAR1 | |
| SCHEMBL3179250 | 0.83 | CYP4F2 (1.00) | CYP4F2CYP4A11LTA4HEPHX2FFAR1 | |
| SCHEMBL1563277 | 0.83 | LTA4H (1.00) | CYP4F2CYP4A11LTA4HEPHX2FFAR1 | |
| SCHEMBL8767634 | 0.82 | KCNA3 (0.61) | CYP4F2CYP4A11LTA4HEPHX2FFAR1 | |
| SCHEMBL17609087 | 0.82 | LTA4H (0.63) | CYP4F2CYP4A11LTA4HEPHX2FFAR1 | |
| SCHEMBL18625341 | 0.82 | CYP4F2 (0.63) | CYP4F2CYP4A11LTA4HEPHX2FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140364398-A1 | C-Linked Hydroxamic Acid Derivatives Useful As Antibacterial Agents | PFIZER INC. (US) | 2014-12-11 | — | — | US | disclosed |
| US-8853258-B2 | C-linked hydroxamic acid derivatives useful as antibacterial agents | PFIZER INC. (US) | 2014-10-07 | — | — | US | disclosed |
| EP-2488489-A2 | C-LINKED HYDROXAMIC ACID DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | Pfizer Inc. (US) | 2012-08-22 | — | — | EP | disclosed |
| US-20120202777-A1 | C-Linked Hydroxamic Acid Derivatives Useful As Antibacterial Agents | BROWN MATTHEW FRANK (US) | 2012-08-09 | — | — | US | disclosed |
| WO-2011045703-A2 | C-LINKED HYDROXAMIC ACID DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | PFIZER INC. (US) | 2011-04-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120202777-A1 | C-Linked Hydroxamic Acid Derivatives Useful As Antibacterial Agents | HAX1, LPXN, AGXT | CYP4F2 3646/4885CYP4A11 4699/4885LTA4H 115/4885 |
| US-20140364398-A1 | C-Linked Hydroxamic Acid Derivatives Useful As Antibacterial Agents | LCT, AGXT, PRXL2A | CYP4F2 3971/4885CYP4A11 4790/4885LTA4H 352/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.