SCHEMBL2286565

SCHEMBL2286565

CS(=O)(=O)c1ccc(S(=O)(=O)CC(=O)ONC(=N)N)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.45
KMT2A Q03164 1/20 0.44
KDM4E B2RXH2 1/20 0.42
NPC1 O15118 1/20 0.41
POLB P06746 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
GSR P00390 2/20 0.38
ENPP2 Q13822 1/20 0.38
MMP1 P03956 1/20 0.38
MMP2 P08253 1/20 0.38
MMP3 P08254 1/20 0.38
MMP7 P09237 1/20 0.38
MMP9 P14780 1/20 0.38
MMP13 P45452 1/20 0.38
MMP14 P50281 1/20 0.38
GAA P10253 1/20 0.37
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA9 Q16790 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8772767 0.88 ALDH1A1 (0.61) ALDH1A1KMT2ACA12CA1CA2
SCHEMBL2289734 0.85 NPC1 (0.61) ALDH1A1KMT2AKDM4ENPC1POLB
SCHEMBL2279847 0.84 HSD11B1 (0.47) ALDH1A1KMT2APOLBMMP1MMP2
SCHEMBL8415493 0.81 HSD11B1 (0.50) ALDH1A1KMT2AKDM4EPOLBMMP1
Guanidine SCHEMBL2286558 0.78 MMP2 (0.54) ALDH1A1NPC1ENPP2MMP2MMP7
SCHEMBL20914731 0.77 ALDH1A1 (0.72) ALDH1A1KMT2AKDM4ENPC1POLB
SCHEMBL10639530 0.75 CA1 (0.47) GAACA12CA1CA2CA9
SCHEMBL5918501 0.72 CA12 (0.39) ALDH1A1GSRENPP2CA12CA1
SCHEMBL3289731 0.71 MMP2 (0.63) ALDH1A1ENPP2MMP2MMP7MMP14
SCHEMBL17550651 0.69 GAA (0.53) ALDH1A1KMT2AKDM4ENPC1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-H691-H CONTAINING IMIDOTHIOESTER COMPOUND AND BASE PRECURSOR; HEAT RESISTANCE, STABILITY, ANTIFOGGING AGENT FUJI PHOTO FILM CO., LTD. (JP) 1989-10-03 US claimed
US-11199776-B2 Resin composition TORAY INDUSTRIES, INC. (JP) 2021-12-14 US disclosed
WO-2019163981-A1 BASE PROLIFERATING AGENT, AND BASE-REACTIVE RESIN COMPOSITION CONTAINING SAID BASE PROLIFERATING AGENT 日本化薬株式会社 2019-08-29 WO disclosed
US-20190241716-A1 RESIN COMPOSITION TORAY INDUSTRIES, INC. (JP) 2019-08-08 US disclosed
US-8877432-B2 Method of forming resist pattern and resist composition TOKYO OHKA KOGYO CO., LTD. (JP) 2014-11-04 US disclosed
EP-2199856-B1 Cationic radiation curable compositions AGFA GRAPHICS NV (BE) 2013-08-07 EP disclosed
US-20110262872-A1 METHOD OF FORMING RESIST PATTERN AND RESIST COMPOSITION TOKYO OHKA KOGYO CO., LTD. (JP) 2011-10-27 US disclosed
US-20110195194-A1 CATIONIC RADIATION CURABLE COMPOSITIONS AGFA GRAPHICS NV (BE) 2011-08-11 US disclosed
WO-2010069754-A1 CATIONIC RADIATION CURABLE COMPOSITIONS AGFA GRAPHICS NV (BE) 2010-06-24 WO disclosed
EP-2199856-A1 Cationic radiation curable compositions Agfa Graphics N.V. (BE) 2010-06-23 EP disclosed
US-4766056-A COLOR SEPARATION AND IMAGE STABILITY FUJI PHOTO FILM CO., LTD. (JP) 1988-08-23 US disclosed
US-4764458-A CONTAINING ORGANIC SILVER SALT OF UNSATURATED AROMATIC CARBOXYLATE FUJI PHOTO FILM CO., LTD. (JP) 1988-08-16 US disclosed
US-4713316-A INFRARED SENSITIZING DYES, MOBILE DYE PRECURSORS, ALKALI, SILVER HALIDE EMULSION FUJI PHOTO FILM CO., LTD. (JP) 1987-12-15 US disclosed
EP-0174634-B1 IMAGE FORMING METHOD FUJI PHOTO FILM CO., LTD. (JP) 1987-12-09 EP disclosed
EP-0228085-A2 Light-sensitive material containing silver halide, reducing agent and polymerizable compound, and image-forming method employing the same FUJI PHOTO FILM CO., LTD. (JP) 1987-07-08 EP disclosed
US-4637975-A CATIONIC DYE FUJI PHOTO FILM CO., LTD. (JP) 1987-01-20 US disclosed
US-4629676-A DRY PROCESSING FUJI PHOTO FILM CO., LTD. (JP) 1986-12-16 US disclosed
EP-0202490-A1 Method for forming a polymer image and image recording material therefor FUJI PHOTO FILM CO., LTD. (JP) 1986-11-26 EP disclosed
EP-0200011-A1 Heat-developable light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1986-11-05 EP disclosed
EP-0192272-A2 Color light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1986-08-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190241716-A1 RESIN COMPOSITION SLC7A1, F12, SLCO2A1 ALDH1A1 1571/4885KMT2A 1240/4885KDM4E 463/4885
US-20110195194-A1 CATIONIC RADIATION CURABLE COMPOSITIONS NR2E3, NR2E1, CCNE2 ALDH1A1 3826/4885KMT2A 2545/4885KDM4E 1553/4885
US-20110262872-A1 METHOD OF FORMING RESIST PATTERN AND RESIST COMPOSITION POLR1A, PARG, POLR1G ALDH1A1 2487/4885KMT2A 742/4885KDM4E 2598/4885
US-11199776-B2 Resin composition SLC7A1, F12, SLCO2A1 ALDH1A1 1571/4885KMT2A 1240/4885KDM4E 463/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.