Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9786958 | 0.80 | SLC6A2 (0.33) | HTR2CHTR2B | |
| SCHEMBL22867762 | 0.69 | HSD17B2 (0.43) | HTR2AHTR2CHTR2BCHRNB2CHRNA4 | |
| SCHEMBL22868095 | 0.68 | KDM4E (0.40) | — | |
| SCHEMBL9786894 | 0.67 | SLC6A2 (0.34) | HTR2AHTR2CHTR2B | |
| SCHEMBL12253322 | 0.65 | NOS3 (0.34) | HTR2AHTR2CHTR2BCHRNB2CHRNA4 | |
| SCHEMBL28302528 | 0.64 | KDM4E (0.31) | — | |
| SCHEMBL13070499 | 0.64 | ACHE (0.38) | HTR2CCHRNB2CHRNA4 | |
| SCHEMBL15896883 | 0.62 | ACHE (0.35) | — | |
| SCHEMBL28226012 | 0.60 | CHRNB2 (0.42) | HTR2AHTR2CHTR2BCHRNB2CHRNA4 | |
| SCHEMBL24446325 | 0.59 | HTR2C (0.40) | HTR2CCHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021003295-A1 | MODULATORS OF HSD17B13 AND METHODS OF USE THEREOF | REGENERON PHARMACEUTICALS, INC. (US) | 2021-01-07 | — | — | WO | disclosed |