SCHEMBL22870546

SCHEMBL22870546

c1ccc2sc(-c3ccc4c5ccc(-c6nc7ccccc7s6)cc5c5nc6c(-c7ccc8c(c7)oc7ccccc78)sc(-c7ccc8c(c7)oc7ccccc78)c6nc5c4c3)nc2c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ APP P05067 5/20 0.44
▸ MAPT P10636 7/20 0.43
▸ ALDH1A1 P00352 7/20 0.43
▸ RAB9A P51151 6/20 0.43
▸ NPC1 O15118 5/20 0.43
▸ KDM4E B2RXH2 5/20 0.43
▸ MEN1 O00255 5/20 0.43
▸ KMT2A Q03164 5/20 0.43
▸ NFKB1 P19838 3/20 0.43
▸ NFKB2 Q00653 3/20 0.43
▸ RELA Q04206 3/20 0.43
▸ MMP9 P14780 1/20 0.43
▸ MMP8 P22894 1/20 0.43
▸ SMN1; SMN2 Q16637 5/20 0.43
▸ HPGD P15428 4/20 0.43
▸ LMNA P02545 3/20 0.43
▸ TP53 P04637 3/20 0.43
▸ HSD17B10 Q99714 3/20 0.43
▸ PKM P14618 1/20 0.43
▸ POLB P06746 3/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20017373 0.87 MAPT (0.53) APPMAPTALDH1A1RAB9ANPC1
SCHEMBL22870936 0.80 GABRP (0.39) MAPTALDH1A1RAB9ANPC1KDM4E
SCHEMBL27258853 0.79 APP (0.49) APPMAPTALDH1A1RAB9ANPC1
SCHEMBL22870731 0.78 PLA2G2A (0.42) MAPTALDH1A1RAB9ANPC1KDM4E
SCHEMBL22870607 0.77 APP (0.41) APPMAPTALDH1A1RAB9ANPC1
SCHEMBL22870521 0.77 RAB9A (0.47) APPMAPTALDH1A1RAB9ANPC1
SCHEMBL12450340 0.77 APP (0.60) APPMAPTALDH1A1RAB9ANPC1
SCHEMBL24332018 0.77 KDM4E (0.48) APPMAPTALDH1A1RAB9ANPC1
SCHEMBL15978780 0.76 MEN1 (0.46) APPMAPTALDH1A1RAB9ANPC1
SCHEMBL30883931 0.76 MEN1 (0.52) APPMAPTALDH1A1RAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12043627-B2 Compound and color conversion film comprising same LG CHEM, LTD. (KR) 2024-07-23 — — US disclosed
US-12043627-B2 Compound and color conversion film comprising same LG CHEM, LTD. (KR) 2024-07-23 — — US disclosed
US-20210002294-A1 COMPOUND AND COLOR CONVERSION FILM COMPRISING SAME LG CHEM, LTD. (KR) 2021-01-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210002294-A1 COMPOUND AND COLOR CONVERSION FILM COMPRISING SAME CRY1, FLI1, FDFT1 APP 265/4885MAPT 645/4885ALDH1A1 47/4885
US-12043627-B2 Compound and color conversion film comprising same CRY1, FLI1, FDFT1 APP 265/4885MAPT 645/4885ALDH1A1 47/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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