SCHEMBL2287698

SCHEMBL2287698

C=CCCCCC(=O)N=CCC

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.47
ABCC4 O15439 1/20 0.47
ALDH1A1 P00352 7/20 0.46
LMNA P02545 3/20 0.46
CYP3A4 P08684 4/20 0.41
USP2 O75604 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
RECQL P46063 2/20 0.41
TSHR P16473 3/20 0.39
HPGD P15428 2/20 0.36
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
F7 P08709 2/20 0.33
F3 P13726 2/20 0.33
FAAH O00519 2/20 0.33
OXER1 Q8TDS5 1/20 0.33
KDM4E B2RXH2 1/20 0.33
FFAR1 O14842 1/20 0.33
NR1I2 O75469 1/20 0.33
PLA2G1B P04054 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7835791 0.79 TERT (0.58) MAPTLMNACYP3A4USP2RECQL
SCHEMBL11038992 0.79 TERT (0.58) MAPTLMNACYP3A4USP2RECQL
SCHEMBL27728573 0.79 CES2 (0.48) ALDH1A1TSHRMEN1KMT2AFFAR1
SCHEMBL2285221 0.77 SMN1; SMN2 (0.44) ALDH1A1LMNASMN1; SMN2TSHRMEN1
SCHEMBL454057 0.75 MAPT (0.57) MAPTABCC4ALDH1A1LMNACYP3A4
SCHEMBL2285953 0.74 ALDH1A1 (0.39) MAPTABCC4ALDH1A1LMNACYP3A4
SCHEMBL5136587 0.73 TERT (0.50) MAPTLMNACYP3A4USP2RECQL
SCHEMBL515388 0.70 MAPT (0.56) MAPTABCC4ALDH1A1LMNACYP3A4
SCHEMBL27744122 0.69 ALDH1A1 (0.47) MAPTALDH1A1LMNACYP3A4USP2
SCHEMBL27764974 0.69 ALDH1A1 (0.47) MAPTALDH1A1LMNACYP3A4USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7994273-B2 Photoactive materials ROLIC AG (CH) 2011-08-09 US claimed
US-7750185-B2 Photoactive materials ROLIC AG (CH) 2010-07-06 US claimed
US-20050288480-A1 Liquid crystals adjustment layers containing diamine compound; polyamic acid or polyimides; crosslinked ROLIC AG (CH) 2005-12-29 US claimed
EP-1525182-A1 PHOTOACTIVE MATERIALS Rolic AG (CH) 2005-04-27 EP claimed
WO-2004013086-A1 PHOTOACTIVE MATERIALS ROLIC AG (CH) 2004-02-12 WO claimed
EP-1386910-A1 Photoactive materials Rolic AG (CH) 2004-02-04 EP claimed
US-8436132-B2 Photoactive materials ROLIC AG (CH) 2013-05-07 US disclosed
US-20110236602-A1 PHOTOACTIVE MATERIALS ROLIC AG (CH) 2011-09-29 US disclosed
US-7994273-B2 Photoactive materials ROLIC AG (CH) 2011-08-09 US disclosed
US-20100272979-A1 PHOTOACTIVE MATERIALS ROLIC AG (CH) 2010-10-28 US disclosed
US-7750185-B2 Photoactive materials ROLIC AG (CH) 2010-07-06 US disclosed
US-20050288480-A1 Liquid crystals adjustment layers containing diamine compound; polyamic acid or polyimides; crosslinked ROLIC AG (CH) 2005-12-29 US disclosed
EP-1525182-A1 PHOTOACTIVE MATERIALS Rolic AG (CH) 2005-04-27 EP disclosed
WO-2004013086-A1 PHOTOACTIVE MATERIALS ROLIC AG (CH) 2004-02-12 WO disclosed
EP-1386910-A1 Photoactive materials Rolic AG (CH) 2004-02-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110236602-A1 PHOTOACTIVE MATERIALS AOC1, CRY1, CCNA1 MAPT 627/4885ABCC4 3778/4885ALDH1A1 129/4885
US-20050288480-A1 Liquid crystals adjustment layers containing diamine compound; polyamic acid or polyimides; crosslinked C9, F12, DAO MAPT 318/4885ABCC4 4717/4885ALDH1A1 1929/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.