SCHEMBL22880485

SCHEMBL22880485

c1ccc(-c2nc3ccc4ccccc4c3nc2-c2cccc3cc4oc5ccccc5c4cc23)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.37
MAPT P10636 4/20 0.37
KMT2A Q03164 4/20 0.36
MAPK1 P28482 2/20 0.36
KDM4E B2RXH2 7/20 0.36
HPGD P15428 3/20 0.36
TSHR P16473 3/20 0.36
HSD17B10 Q99714 3/20 0.36
ALOX15 P16050 1/20 0.36
CASP1 P29466 1/20 0.36
CASP7 P55210 1/20 0.36
MEN1 O00255 2/20 0.36
LMNA P02545 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
L3MBTL1 Q9Y468 4/20 0.35
CYP2A6 P11509 1/20 0.34
ESR1 P03372 2/20 0.34
ESR2 Q92731 2/20 0.34
AHR P35869 1/20 0.33
CHEK2 O96017 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22880475 0.96 ALDH1A1 (0.37) ALDH1A1MAPTKMT2AMAPK1KDM4E
SCHEMBL22880470 0.96 ALDH1A1 (0.37) ALDH1A1MAPTKMT2AMAPK1KDM4E
SCHEMBL26217069 0.89 CHEK2 (0.38) ALDH1A1MAPTKMT2AMAPK1KDM4E
SCHEMBL26217070 0.89 CHEK2 (0.38) ALDH1A1MAPTKMT2AMAPK1KDM4E
SCHEMBL22880174 0.88 L3MBTL1 (0.44) ALDH1A1MAPTKMT2AMAPK1KDM4E
SCHEMBL22880179 0.85 MAPT (0.39) ALDH1A1MAPTKMT2AMAPK1KDM4E
SCHEMBL22880242 0.85 MAPT (0.39) ALDH1A1MAPTKMT2AMAPK1KDM4E
SCHEMBL22880277 0.84 ADORA2A (0.38) ALDH1A1MAPTKMT2AMAPK1KDM4E
SCHEMBL22880446 0.84 ADORA2A (0.38) ALDH1A1MAPTKMT2AMAPK1KDM4E
SCHEMBL22880094 0.84 ADORA2A (0.38) ALDH1A1MAPTKMT2AMAPK1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230345827-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2023-10-26 US disclosed
US-20230345827-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2023-10-26 US disclosed
US-11793075-B2 Plurality of host materials and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. 2023-10-17 US disclosed
US-11793075-B2 Plurality of host materials and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. 2023-10-17 US disclosed
US-20230126428-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2023-04-27 US disclosed
US-20230126428-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2023-04-27 US disclosed
US-11552257-B2 Plurality of host materials and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. 2023-01-10 US disclosed
US-20220131081-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2022-04-28 US disclosed
US-20210028373-A1 A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2021-01-28 US disclosed
US-20210020849-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2021-01-21 US disclosed
US-20210013427-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2021-01-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210028373-A1 A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME TERT, TELO2, LIMS1 ALDH1A1 487/4885MAPT 1849/4885KMT2A 2746/4885
US-20220131081-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME LEF1, ODC1, TMEM109 ALDH1A1 45/4885MAPT 2469/4885KMT2A 2186/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.