Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18366439 | 0.70 | MAPT (0.40) | — | |
| SCHEMBL21033478 | 0.65 | PDE10A (0.33) | PDE4B | |
| SCHEMBL18365963 | 0.63 | ASPH (0.33) | — | |
| SCHEMBL30587606 | 0.62 | ALDH1A1 (0.38) | — | |
| SCHEMBL20356642 | 0.61 | PKM (0.42) | — | |
| SCHEMBL28759933 | 0.60 | CA2 (0.42) | — | |
| SCHEMBL22056199 | 0.58 | EGLN2 (0.36) | — | |
| SCHEMBL18189827 | 0.57 | GRIA1 (0.51) | — | |
| SCHEMBL11784400 | 0.57 | ALDH1A1 (0.39) | PDE4B | |
| SCHEMBL25153650 | 0.57 | ALDH1A1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3760625-A1 | BICYCLIC LACTAMS AS RECEPTOR-INTERACTING PROTEIN-1 (RIP1) KINASE INHIBITORS FOR TREATING E.G. INFLAMMATORY DISEASES | F. Hoffmann-La Roche AG (CH) | 2021-01-06 | — | — | EP | disclosed |