Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.36 |
| ▸ | NOTCH1 | P46531 | 1/20 | 0.36 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | CCR2 | P41597 | 2/20 | 0.34 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22891783 | 0.82 | TAS2R14 (0.40) | TAS2R14GAANPSR1MEN1KMT2A | |
| SCHEMBL22891787 | 0.82 | NPSR1 (0.49) | GAANPSR1KMT2AALDH1A1HPGD | |
| SCHEMBL29670020 | 0.69 | ERAP1 (0.46) | GAAMAPTNPSR1KMT2AKDM4E | |
| SCHEMBL9299353 | 0.64 | HPGD (0.60) | GAAMAPTTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL6566141 | 0.63 | ALDH1A1 (0.53) | MAPTATMKMT2AALOX15ALDH1A1 | |
| SCHEMBL22891786 | 0.63 | NPSR1 (0.49) | GAATSHRNPSR1MEN1KMT2A | |
| SCHEMBL29669997 | 0.63 | NPSR1 (0.49) | GAATSHRNPSR1MEN1KMT2A | |
| SCHEMBL25805521 | 0.61 | DDR2 (0.58) | TAS2R14GAA | |
| SCHEMBL18615685 | 0.60 | EPHX2 (0.62) | GAAMAPTTSHRMEN1KMT2A | |
| SCHEMBL8414315 | 0.60 | MMP9 (0.47) | MAPTNPSR1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021007474-A1 | PHENYL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC APPLICATIONS | CURA THERAPEUTICS, LLC (US) | 2021-01-14 | — | — | WO | disclosed |